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DAZAP1 Antikörper (Middle Region)

DAZAP1 Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Zebrafisch (Danio rerio), Pferd, Rind (Kuh) WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2779144
  • Target Alle DAZAP1 Antikörper anzeigen
    DAZAP1 (DAZ Associated Protein 1 (DAZAP1))
    Bindungsspezifität
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    • 26
    • 13
    • 9
    • 7
    • 6
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    Human, Maus, Ratte, Hund, Meerschweinchen, Zebrafisch (Danio rerio), Pferd, Rind (Kuh)
    Wirt
    • 24
    • 4
    Kaninchen
    Klonalität
    • 23
    • 5
    Polyklonal
    Konjugat
    • 24
    • 2
    • 1
    • 1
    Dieser DAZAP1 Antikörper ist unkonjugiert
    Applikation
    • 21
    • 11
    • 8
    • 6
    • 4
    • 4
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    GKKVEVKRAE PRDSKSQAPG QPGASQWGSR VVPNAANGWA GQPPPTWQQG
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rat: 100%, Zebrafish: 85%
    Produktmerkmale
    This is a rabbit polyclonal antibody against DAZAP1. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human DAZAP1
    Top Product
    Discover our top product DAZAP1 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 401 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    DAZAP1 (DAZ Associated Protein 1 (DAZAP1))
    Andere Bezeichnung
    DAZAP1 (DAZAP1 Produkte)
    Synonyme
    MGC89358 antikoerper, DAZAP1 antikoerper, 2410042M16Rik antikoerper, mPrrp antikoerper, DAZ associated protein 1 antikoerper, DAZ associated protein 1 L homeolog antikoerper, dazap1 antikoerper, DAZAP1 antikoerper, Dazap1 antikoerper, dazap1.L antikoerper
    Hintergrund
    In mammals, the Y chromosome directs the development of the testes and plays an important role in spermatogenesis. A high percentage of infertile men have deletions that map to regions of the Y chromosome. The DAZ (deleted in azoospermia) gene cluster maps to the AZFc region of the Y chromosome and is deleted in many azoospermic and severely oligospermic men. It is thought that the DAZ gene cluster arose from the transposition, amplification, and pruning of the ancestral autosomal gene DAZL also involved in germ cell development and gametogenesis. DAZAP1 is a RNA-binding protein with two RNP motifs that was originally identified by its interaction with the infertility factors DAZ and DAZL. Two isoforms are encoded by transcript variants of this gene.In mammals, the Y chromosome directs the development of the testes and plays an important role in spermatogenesis. A high percentage of infertile men have deletions that map to regions of the Y chromosome. The DAZ (deleted in azoospermia) gene cluster maps to the AZFc region of the Y chromosome and is deleted in many azoospermic and severely oligospermic men. It is thought that the DAZ gene cluster arose from the transposition, amplification, and pruning of the ancestral autosomal gene DAZL also involved in germ cell development and gametogenesis. This gene encodes a RNA-binding protein with two RNP motifs that was originally identified by its interaction with the infertility factors DAZ and DAZL. Two isoforms are encoded by transcript variants of this gene.
    Alias Symbols: MGC19907
    Protein Interaction Partner: UBC, WWOX, RPA3, RPA2, RPA1, SUZ12, RNF2, EZH2, BMI1, rev, ITCH, RAD52, VCAM1, ITGA4, FN1, BRCA1, CAND1, COPS5, CUL1, CUL2, CUL3, CUL4B, CUL5, NEDD8, ELAVL1, SUMO2, DAZ1, DAZL,
    Protein Size: 401
    Molekulargewicht
    43 kDa
    Gen-ID
    26528
    NCBI Accession
    NM_018959, NP_061832
    UniProt
    Q96EP5
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