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DIS3 Antikörper (N-Term)

DIS3 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen, Hund, Pferd, Meerschweinchen, Schwein WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2779073
  • Target Alle DIS3 Antikörper anzeigen
    DIS3 (Exosome Complex Exonuclease RRP44 (DIS3))
    Bindungsspezifität
    • 8
    • 8
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 44
    • 15
    • 7
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Maus, Ratte, Rind (Kuh), Kaninchen, Hund, Pferd, Meerschweinchen, Schwein
    Wirt
    • 39
    • 5
    Kaninchen
    Klonalität
    • 42
    • 2
    Polyklonal
    Konjugat
    • 24
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser DIS3 Antikörper ist unkonjugiert
    Applikation
    • 33
    • 22
    • 15
    • 7
    • 6
    • 4
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    DIVAVELLPK SQWVAPSSVV LHDEGQNEED VEKEEETERM LKTAVSEKML
    Homologie
    Cow: 79%, Dog: 93%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Mouse: 85%, Pig: 93%, Rabbit: 86%, Rat: 86%
    Produktmerkmale
    This is a rabbit polyclonal antibody against DIS3. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human DIS3
    Top Product
    Discover our top product DIS3 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 958 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    DIS3 (Exosome Complex Exonuclease RRP44 (DIS3))
    Andere Bezeichnung
    DIS3 (DIS3 Produkte)
    Synonyme
    EXOSC11 antikoerper, KIAA1008 antikoerper, RP11-342J4.3 antikoerper, RRP44 antikoerper, bA555G22.1 antikoerper, dis3p antikoerper, DIS3 antikoerper, 2810028N01Rik antikoerper, RGD1304646 antikoerper, wu:fb08g12 antikoerper, dis3 antikoerper, DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease antikoerper, DIS3 exosome endoribonuclease and 3'-5' exoribonuclease antikoerper, DIS3 antikoerper, Dis3 antikoerper, dis3 antikoerper, dis3.L antikoerper
    Hintergrund
    DIS3, belonging to the ribonuclease II (RNB) family, has a 3'-5' exonuclease activity. It is a catalytic component of the exosome 3'->5' exoribonuclease complex required for the 3'-processing of the 7S pre-RNA to the mature 5.8S rRNA and for mRNA decay. The protein is implicated in mitotic control and essential for cell division and spore germination. It may be involved in regulating protein dephosphorylation during mitosis.
    Alias Symbols: DKFZp667L1817, FLJ10484, KIAA1008, MGC33035, RP11-342J4.3, RRP44, bA555G22.1, dis3p, EXOSC11
    Protein Interaction Partner: SUMO2, UBC, TWF1, NTMT1, EXOSC8, EXOSC10, AICDA, WDR1, STXBP3, PPP5C, SH3PXD2B, EXOSC5, EXOSC4, EXOSC1, EXOSC3, SKIV2L2, EXOSC2, EXOSC7, DIS3, EXOSC9, CUL3, CUL5, SIRT7, BABAM1, EXOSC6, MPP6, ZBTB17,
    Protein Size: 958
    Molekulargewicht
    109 kDa
    Gen-ID
    22894
    NCBI Accession
    NM_014953, NP_055768
    UniProt
    Q9Y2L1
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