AARS Antikörper (N-Term)

Produktnummer ABIN2778779

Produktdetails anti-AARS Antikörper

Target: AARS (Alanyl tRNA Synthetase (AARS))

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte, Maus, Meerschweinchen, Pferd, Kaninchen, Rind (Kuh), Zebrafisch (Danio rerio), Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AARS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: DSTLTASEIR QRFIDFFKRN EHTYVHSSAT IPLDDPTLLF ANAGMNQFKP

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against AARS. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human AARS

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 968 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu AARS

Target: AARS (Alanyl tRNA Synthetase (AARS))

Andere Bezeichnung: AARS (AARS Produkte)

Synonyme: im:7146712 antikoerper, si:ch211-223o1.6 antikoerper, wu:fc48h07 antikoerper, zgc:113920 antikoerper, CMT2N antikoerper, AI316495 antikoerper, C76919 antikoerper, sti antikoerper, alanyl-tRNA synthetase antikoerper, alanyl-tRNA synthetase L homeolog antikoerper, aars antikoerper, aars.L antikoerper, AARS antikoerper, Aars antikoerper, LOC693023 antikoerper

Hintergrund: The human alanyl-tRNA synthetase (AARS) belongs to a family of tRNA synthases, of the class II enzymes. Class II tRNA synthases evolved early in evolution and are highly conserved. This is reflected by the fact that 498 of the 968-residue polypeptide human AARS shares 41 % identity witht the E.coli protein. tRNA synthases are the enzymes that interpret the RNA code and attach specific aminoacids to the tRNAs that contain the cognate trinucleotide anticodons. They consist of a catalytic domain which interacts with the amino acid acceptor-T psi C helix of the tRNA, and a second domain which interacts with the rest of the tRNA structure. The human alanyl-tRNA synthetase (AARS) belongs to a family of tRNA synthases, of the class II enzymes. Class II tRNA synthases evolved early in evolution and are highly conserved. This is reflected by the fact that 498 of the 968-residue polypeptide human AARS shares 41 % identity witht the E.coli protein. tRNA synthases are the enzymes that interpret the RNA code and attach specific aminoacids to the tRNAs that contain the cognate trinucleotide anticodons. They consist of a catalytic domain which interacts with the amino acid acceptor-T psi C helix of the tRNA, and a second domain which interacts with the rest of the tRNA structure.
Alias Symbols: CMT2N
Protein Interaction Partner: ISG15, UBC, SUMO2, SUMO1, NEDD8, TPD52, STAT5B, SRP9, PPP2R5E, METTL1, HSF1, CALU, DPP9, NIF3L1, ANKMY2, DPP8, IPO11, EEF2K, CACYBP, ARPC1B, SAE1, TOM1L1, EIF4A3, WARS, TPD52L2, UBD, VCAM1, ITGA4, HSP90AB1, HSP90AA1, FN1, NSUN2, LARS, FARSB, UBA1, QARS, N
Protein Size: 968

Molekulargewicht: 107 kDa

Gen-ID: 16

NCBI Accession: NM_001605, NP_001596

UniProt: P49588