TCF7L2 Antikörper (N-Term)

Produktnummer ABIN2778365

Produktdetails anti-TCF7L2 Antikörper

Target: TCF7L2 (Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) (TCF7L2))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TCF7L2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MPQLNGGGGD DLGANDELIS FKDEGEQEEK SSENSSAERD LADVKSSLVN

Homologie: Cow: 100%, Dog: 75%, Guinea Pig: 75%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against Tcf7l2. It was validated on Western Blot.

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TCF7L2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 459 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TCF7L2

Target: TCF7L2 (Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) (TCF7L2))

Andere Bezeichnung: Tcf7l2 (TCF7L2 Produkte)

Synonyme: TCF4B antikoerper, TCF4E antikoerper, Tcf-4 antikoerper, Tcf4 antikoerper, mTcf-4B antikoerper, mTcf-4E antikoerper, tcf4 antikoerper, XTCF-4 antikoerper, tcf4e antikoerper, TCF4 antikoerper, TCF-4 antikoerper, TCFL2 antikoerper, transcription factor 7 like 2 antikoerper, transcription factor 7-like 2 antikoerper, transcription factor 7 like 2, T cell specific, HMG box antikoerper, transcription factor 7 like 2 L homeolog antikoerper, transcription factor 7-like 2 (T-cell specific, HMG-box) antikoerper, TCF7L2 antikoerper, LOC100545943 antikoerper, Tcf7l2 antikoerper, tcf7l2 antikoerper, tcf7l2.L antikoerper

Hintergrund: This gene encodes a high mobility group (HMG) box-containing transcription factor that plays a key role in the Wnt signaling pathway. The protein has been implicated in blood glucose homeostasis. Genetic variants of this gene are associated with increased risk of type 2 diabetes. Several transcript variants encoding multiple different isoforms have been found for this gene.
Alias Symbols: TCF4, TCF-4
Protein Interaction Partner: Ctnnb1, Hdac1, Hdac2, Hnf4a,
Protein Size: 619

Molekulargewicht: 68 kDa

Gen-ID: 6934

NCBI Accession: XM_005270084, XP_005270141

UniProt: Q9NQB0

Pathways: WNT Signalweg, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Regulation of Hormone Metabolic Process, Carbohydrate Homeostasis, Stem Cell Maintenance, Protein targeting to Nucleus