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AFF3 Antikörper (Middle Region)

AFF3 Reaktivität: Human, Maus, Ratte, Schwein, Kaninchen, Hund WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2778345
  • Target Alle AFF3 Antikörper anzeigen
    AFF3 (AF4/FMR2 Family, Member 3 (AFF3))
    Bindungsspezifität
    • 3
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    • 8
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Schwein, Kaninchen, Hund
    Wirt
    • 8
    Kaninchen
    Klonalität
    • 8
    Polyklonal
    Konjugat
    • 8
    Dieser AFF3 Antikörper ist unkonjugiert
    Applikation
    • 7
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    APATKDSESA PPSHTSDTPA EKALPKSKRK RKCDNEDDYR EIKKSQGEKD
    Homologie
    Dog: 86%, Human: 100%, Mouse: 93%, Pig: 86%, Rabbit: 77%, Rat: 93%
    Produktmerkmale
    This is a rabbit polyclonal antibody against AFF3. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human AFF3
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 1226 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • To, Faseruk, Gokgoz, Pinnaduwage, Done, Andrulis: "LAF-4 is aberrantly expressed in human breast cancer." in: International journal of cancer. Journal international du cancer, Vol. 115, Issue 4, pp. 568-74, (2005) (PubMed).

  • Target
    AFF3 (AF4/FMR2 Family, Member 3 (AFF3))
    Andere Bezeichnung
    AFF3 (AFF3 Produkte)
    Synonyme
    id:ibd5053 antikoerper, LAF4 antikoerper, MLLT2-like antikoerper, 3222402O04Rik antikoerper, A730046J16 antikoerper, LAF-4 antikoerper, Laf4 antikoerper, AF4/FMR2 family member 3 antikoerper, AF4/FMR2 family, member 3 antikoerper, AFF3 antikoerper, aff3 antikoerper, Aff3 antikoerper
    Hintergrund
    AFF3 is a tissue-restricted nuclear transcriptional activator that is preferentially expressed in lymphoid tissue. Isolation of this protein initially defined a highly conserved LAF4/MLLT2 gene family of nuclear transcription factors that may function in lymphoid development and oncogenesis. In some ALL patients, this gene has been found fused to the gene for MLL.This gene encodes a tissue-restricted nuclear transcriptional activator that is preferentially expressed in lymphoid tissue. Isolation of this protein initially defined a highly conserved LAF4/MLLT2 gene family of nuclear transcription factors that may function in lymphoid development and oncogenesis. In some ALL patients, this gene has been found fused to the gene for MLL. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene.
    Alias Symbols: LAF4, MLLT2-like
    Protein Interaction Partner: CDK9, MLLT3,
    Protein Size: 1226
    Molekulargewicht
    133 kDa
    Gen-ID
    3899
    NCBI Accession
    NM_002285, NP_002276
    UniProt
    P51826
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