XRCC5 Antikörper (C-Term)
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- Target Alle XRCC5 Antikörper anzeigen
- XRCC5 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 5 (Double-Strand-Break Rejoining) (XRCC5))
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Bindungsspezifität
- C-Term
- Reaktivität
- Human, Maus, Ratte, Hund, Pferd, Rind (Kuh), Meerschweinchen, Kaninchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser XRCC5 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequenz
- GITLITKEEA SGSSVTAEEA KKFLAPKDKP SGDTAAVFEE GGDVDDLLDM
- Homologie
- Cow: 92%, Dog: 92%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 85%, Rabbit: 93%, Rat: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against XRCC5. It was validated on Western Blot and immunohistochemistry.
- Aufreinigung
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human XRCC5
- Top Product
- Discover our top product XRCC5 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 732 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- XRCC5 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 5 (Double-Strand-Break Rejoining) (XRCC5))
- Andere Bezeichnung
- XRCC5 (XRCC5 Produkte)
- Synonyme
- AI314015 antikoerper, Ku80 antikoerper, Ku86 antikoerper, Kup80 antikoerper, KARP-1 antikoerper, KARP1 antikoerper, KU80 antikoerper, KUB2 antikoerper, NFIV antikoerper, xrcc5-a antikoerper, XRCC5 antikoerper, X-ray repair cross complementing 5 antikoerper, X-ray repair complementing defective repair in Chinese hamster cells 5 antikoerper, X-ray repair complementing defective repair in Chinese hamster cells 5 L homeolog antikoerper, XRCC5 antikoerper, Xrcc5 antikoerper, xrcc5.L antikoerper
- Hintergrund
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XRCC5 encodes the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
Alias Symbols: KU80, KUB2, Ku86, NFIV, KARP1, KARP-1
Protein Interaction Partner: HUWE1, UBC, EHF, ELF3, SUMO2, SUMO3, BRCA1, ATRX, Fbxl16, NEDD8, SUMO1, MDM2, RPA3, RPA2, RPA1, SUZ12, EED, RNF2, BMI1, EIF4B, C1QBP, RPL24, PLCB3, PRMT3, EIF3J, CUL2, CSDE1, SF1, TRMT1, SAMHD1, DNMBP, GANAB, HYOU1, NCL, NARS, MSH2, JUP, HSPA4, PARP1, TAR
Protein Size: 732 - Molekulargewicht
- 83 kDa
- Gen-ID
- 7520
- NCBI Accession
- NM_021141, NP_066964
- UniProt
- Q4VBQ5
- Pathways
- DNA Reparatur
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