PTGER3 Antikörper (Middle Region)

Produktnummer ABIN2778265

Produktdetails anti-PTGER3 Antikörper

Target: PTGER3 (Prostaglandin E Receptor 3 (Subtype EP3) (PTGER3))

Bindungsspezifität: Middle Region

Reaktivität: Human, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PTGER3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: ILDPWVYLLL RKILLRKFCQ IRYHTNNYAS SSTSLPCQCS STLMWSDHLE

Homologie: Horse: 100%, Human: 100%, Rabbit: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PTGER3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PTGER3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 390 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PTGER3

Target: PTGER3 (Prostaglandin E Receptor 3 (Subtype EP3) (PTGER3))

Andere Bezeichnung: PTGER3 (PTGER3 Produkte)

Synonyme: PTGER3 antikoerper, EP3 antikoerper, EP3-I antikoerper, EP3-II antikoerper, EP3-III antikoerper, EP3-IV antikoerper, EP3e antikoerper, PGE2-R antikoerper, PTGEREP3 antikoerper, Rep3 antikoerper, rEP3a antikoerper, rEP3b antikoerper, Pgerep3 antikoerper, Ptgerep3 antikoerper, prostaglandin E receptor 3 antikoerper, prostaglandin E receptor 3 L homeolog antikoerper, prostaglandin E receptor 3 (subtype EP3) antikoerper, PTGER3 antikoerper, ptger3.L antikoerper, Ptger3 antikoerper

Hintergrund: PTGER3 is the receptor for prostaglandin E2 (PGE2), the EP3 receptor may be involved in inhibition of gastric acid secretion, modulation of neurotransmitter release in central and peripheral neurons, inhibition of sodium and water reabsorption in kidney tubulus and contraction in uterine smooth muscle. The activity of this receptor can couple to both the inhibition of adenylate cyclase mediated by G-I proteins, and to an elevation of intracellular calcium. The various isoforms have identical ligand binding properties but can interact with different second messenger systems.The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor may have many biological functions, which involve digestion, nervous system, kidney reabsorption, and uterine contraction activities. Studies of the mouse counterpart suggest that this receptor may also mediate adrenocorticotropic hormone response as well as fever generation in response to exogenous and endogenous stimuli. Multiple alternatively spliced transcript variants encoding eight distinct isoforms have been reported.
Alias Symbols: EP3, EP3-I, EP3-II, EP3-III, EP3-IV, EP3e, MGC141828, MGC141829, MGC27302, PGE2-R
Protein Interaction Partner: NOTCH2NL, INCA1, KRTAP10-3, KRTAP10-8, KRTAP10-9, KRTAP10-7, TRIM42, MGAT5B, KRT40, CCDC33, ADAMTSL4, EFEMP2, RGS17, SPRY2, KRT38, RGS20, TCF4, REL, MEOX2, KRT31, CDA, GHRL, MKLN1, PTGER1,
Protein Size: 390

Molekulargewicht: 43 kDa

Gen-ID: 5733

NCBI Accession: NM_198719, NP_942012

UniProt: P43115