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BCL11B Antikörper (Middle Region)

BCL11B Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Meerschweinchen, Pferd WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2777845
  • Target Alle BCL11B Antikörper anzeigen
    BCL11B (B-Cell CLL/lymphoma 11B (Zinc Finger Protein) (BCL11B))
    Bindungsspezifität
    • 9
    • 7
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    • 48
    • 8
    • 7
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Meerschweinchen, Pferd
    Wirt
    • 47
    • 1
    • 1
    • 1
    Kaninchen
    Klonalität
    • 39
    • 11
    Polyklonal
    Konjugat
    • 28
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Dieser BCL11B Antikörper ist unkonjugiert
    Applikation
    • 28
    • 15
    • 11
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    QASKLKRHMK THMHKAGSLA GRSDDGLSAA SSPEPGTSEL AGEGLKAADG
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against BCL11B. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human BCL11B
    Top Product
    Discover our top product BCL11B Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 823 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    BCL11B (B-Cell CLL/lymphoma 11B (Zinc Finger Protein) (BCL11B))
    Andere Bezeichnung
    BCL11B (BCL11B Produkte)
    Synonyme
    BCL11B antikoerper, 9130430L19Rik antikoerper, AI604821 antikoerper, B630002E05Rik antikoerper, BCL-11B antikoerper, Ctip2 antikoerper, Rit1 antikoerper, ATL1 antikoerper, ATL1-alpha antikoerper, ATL1-beta antikoerper, ATL1-delta antikoerper, ATL1-gamma antikoerper, CTIP-2 antikoerper, CTIP2 antikoerper, RIT1 antikoerper, ZNF856B antikoerper, hRIT1-alpha antikoerper, B-cell CLL/lymphoma 11B antikoerper, B cell leukemia/lymphoma 11B antikoerper, B-cell CLL/lymphoma 11B (zinc finger protein) antikoerper, BCL11B antikoerper, Bcl11b antikoerper
    Hintergrund
    BCL11B is the tumor-suppressor protein involved in T-cell lymphomas. BCL11B may function on the P53-signaling pathway. BCL11B may be a key regulator of both differentiation and survival during thymocyte development. BCL11B repress transcription through direct, TFCOUP2-independent binding to a GC-rich response element.This gene encodes a C2H2-type zinc finger protein and is closely related to BCL11A, a gene whose translocation may be associated with B-cell malignancies. The specific function of this gene has not yet been determined. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported.
    Alias Symbols: CTIP-2, CTIP2, RIT1, hRIT1-alpha, ZNF856B
    Protein Interaction Partner: HDAC6, HDAC2, HDAC1, NOTCH1, UBC, HDAC3, SUV39H1, tat, CBX5, NR2F1, SP1, MBD3, MTA2, MTA1, RBBP7, RBBP4, CHD4, NR2F2,
    Protein Size: 823
    Molekulargewicht
    88 kDa
    Gen-ID
    64919
    NCBI Accession
    NM_022898, NP_075049
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