Early B-Cell Factor 4 (EBF4) (Middle Region) Antikörper

Details zu Produkt Nr. ABIN2777680, Anbieter: Anmelden zum Anzeigen
Antigen
  • Ebf3
  • O/E-4
  • Olf-1
  • COE4
  • early B-cell factor 4
  • early B cell factor 4
  • EBF4
  • Ebf4
Epitop
Middle Region
5
2
2
1
1
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus), Zebrafisch (Danio rerio)
15
11
9
7
6
6
5
5
5
3
2
1
1
1
Wirt
Kaninchen
14
2
Klonalität
Polyklonal
Applikation
Western Blotting (WB)
16
4
Optionen
Hersteller
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Immunogen The immunogen is a synthetic peptide directed towards the middle region of human EBF4
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN976098.
Sequenz STAAQSGVGL ARAHFEKQPP SNLRKSNFFH FVLAMYDRQG QPVEVERTAF
Spezifität 100 % homologous to both isoforms of hEBF4.
Homologie Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
Produktmerkmale This is a rabbit polyclonal antibody against EBF4. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Antigen
Andere Bezeichnung EBF4 (EBF4 Antibody Abstract)
Hintergrund EBF4 belongs to the COE family and contains 1 IPT/TIG domain. EBF4 is a transcriptional factor which recognizes variations of the palindromic sequence 5'-ATTCCCNNGGGAATT-3'. EBF4 belongs to the conserved Olf/EBF family of helix-loop-helix transcription factors, members of which play important roles in neural development and B-cell maturation (Wang et al., 2002 [PubMed 12139918]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-131 AB037863.1 1-131 132-137 AL035460.15 8605-8610 138-911 AB037863.1 132-905 912-2904 BC037555.1 12-2004 2905-2931 BC054347.1 1559-1585
Alias Symbols: COE4, KIAA1442, O/E-4, RP5-860F19.3
Protein Interaction Partner: CDK6, APP, LNX1,
Protein Size: 598
Molekulargewicht 64 kDa
Gen-ID 57593
NCBI Accession NM_001110514, NP_001103984
UniProt Q9BQW3
Applikations-hinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 598 AA

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Bilder des Herstellers
Western Blotting (WB) image for anti-Early B-Cell Factor 4 (EBF4) (Middle Region) antibody (ABIN2777680) WB Suggested Anti-EBF4 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Posi...
Produkt verwendet in: Zheng, Hu, Huang, Wang, Lu: "[Effects of SCL antisense ooligonucleotides on K562 and CEM cell lines]." in: Zhongguo shi yan xue ye xue za zhi / Zhongguo bing li sheng li xue hui = Journal of experimental hematology / Chinese Association of Pathophysiology, Vol. 10, Issue 5, pp. 404-8, 2003 (PubMed).

Allgemeine Veröffentlichungen Wang, Betz, Reed: "Cloning of a novel Olf-1/EBF-like gene, O/E-4, by degenerate oligo-based direct selection." in: Molecular and cellular neurosciences, Vol. 20, Issue 3, pp. 404-14, 2002 (PubMed).

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