NR5A1 Antikörper (Middle Region)

Produktnummer ABIN2777447

Produktdetails anti-NR5A1 Antikörper

Target: NR5A1 (Nuclear Receptor Subfamily 5, Group A, Member 1 (NR5A1))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Meerschweinchen, Pferd, Kaninchen, Hund, Rind (Kuh), Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NR5A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: AVPGAHGPLA GYLYPAFPGR AIKSEYPEPY ASPPQPGLPY GYPEPFSGGP

Homologie: Cow: 92%, Dog: 92%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 79%, Rabbit: 85%, Rat: 92%, Sheep: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against NR5A1. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human NR5A1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 461 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu NR5A1

Target: NR5A1 (Nuclear Receptor Subfamily 5, Group A, Member 1 (NR5A1))

Andere Bezeichnung: NR5A1 (NR5A1 Produkte)

Synonyme: AD4BP antikoerper, ELP antikoerper, FTZ1 antikoerper, FTZF1 antikoerper, POF7 antikoerper, SF-1 antikoerper, SF1 antikoerper, SPGF8 antikoerper, SRXY3 antikoerper, Ad4BP antikoerper, ELP-3 antikoerper, Ftz-F1 antikoerper, Ftzf1 antikoerper, Ad4BP/SF-1 antikoerper, Ad4bp antikoerper, Sf-1 antikoerper, NR5A1 antikoerper, sf-1 antikoerper, elp antikoerper, sf1 antikoerper, ftz1 antikoerper, ad4bp antikoerper, ftzf1 antikoerper, SF-1/Ad4BP antikoerper, SI:zC167P9.2 antikoerper, ff1d antikoerper, nr5a2l antikoerper, nuclear receptor subfamily 5 group A member 1 antikoerper, nuclear receptor subfamily 5, group A, member 1 antikoerper, nuclear receptor subfamily 5 group A member 1 L homeolog antikoerper, nuclear receptor subfamily 6 group A member 1 antikoerper, nuclear receptor subfamily 5, group A, member 1b antikoerper, NR5A1 antikoerper, Nr5a1 antikoerper, nr5a1.L antikoerper, nr5a1 antikoerper, NR6A1 antikoerper, nr5a1b antikoerper

Hintergrund: NR5A1 is an important regulator of steroidogeneisis which is present in human skin and its appendages. It plays a role in regulating p450scc expression with TReP-132 and CBP/p300. The protein encoded by this gene is a transcriptional activator involved in sex determination. The encoded protein binds DNA as a monomer. Defects in this gene are a cause of XY sex reversal with or without adrenal failure as well as adrenocortical insufficiency without ovarian defect. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: AD4BP, ELP, FTZ1, FTZF1, SF-1, SF1, POF7, SPGF8, SRXY3
Protein Interaction Partner: NCK2, NR0B1, RAD54L2, THOC2, ALYREF, EIF4A3, DDX39B, UBC, BARD1, ELAVL1, TCF7L2, CTNNB1, CREBBP, CXXC1, PNRC2, SOX8, PIAS1, ZNF653, TRERF1, EDF1, GATA4, GTF2B, SOX2, SOX9, TBX19, NCOA1, NRIP1, PITX1, SMARCD3, PROX1, AR, SP1, NFYA, MAPK1, JUN, NFKB2,
Protein Size: 461

Molekulargewicht: 52 kDa

Gen-ID: 2516

NCBI Accession: NM_004959, NP_004950

UniProt: Q13285

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Maintenance of Protein Location