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ESR2 Antikörper (N-Term)

ESR2 Reaktivität: Human, Maus, Ratte, Schaf, Schwein, Pferd, Hund, Rind (Kuh), Kaninchen, Meerschweinchen, Ziege WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2777397
  • Target Alle ESR2 Antikörper anzeigen
    ESR2 (Estrogen Receptor 2 (ESR2))
    Bindungsspezifität
    • 28
    • 18
    • 16
    • 16
    • 13
    • 8
    • 8
    • 7
    • 7
    • 7
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 190
    • 112
    • 93
    • 31
    • 18
    • 16
    • 14
    • 6
    • 5
    • 4
    • 4
    • 2
    • 1
    Human, Maus, Ratte, Schaf, Schwein, Pferd, Hund, Rind (Kuh), Kaninchen, Meerschweinchen, Ziege
    Wirt
    • 167
    • 36
    • 1
    • 1
    Kaninchen
    Klonalität
    • 160
    • 45
    Polyklonal
    Konjugat
    • 93
    • 18
    • 15
    • 9
    • 8
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ESR2 Antikörper ist unkonjugiert
    Applikation
    • 171
    • 76
    • 55
    • 39
    • 38
    • 26
    • 26
    • 19
    • 11
    • 11
    • 10
    • 10
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    TPGHLSPLVV HRQLSHLYAE PQKSPWCEAR SLEHTLPVNR ETLKRKVSGN
    Spezifität
    Directed towards isoforms 1-8.
    Homologie
    Cow: 100%, Dog: 93%, Goat: 93%, Guinea Pig: 93%, Horse: 79%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 85%, Rat: 100%, Sheep: 93%
    Produktmerkmale
    This is a rabbit polyclonal antibody against ESR2. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human ESR2
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 530 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    ESR2 (Estrogen Receptor 2 (ESR2))
    Andere Bezeichnung
    ESR2 (ESR2 Produkte)
    Synonyme
    ER-BETA antikoerper, ESR-BETA antikoerper, ESRB antikoerper, ESTRB antikoerper, Erb antikoerper, NR3A2 antikoerper, ER[b]1 antikoerper, zfER-beta1 antikoerper, zfER[b]1 antikoerper, erb2 antikoerper, CERB antikoerper, ERB antikoerper, erb antikoerper, esrb antikoerper, estrb antikoerper, nr3a2 antikoerper, ERbeta antikoerper, er-beta antikoerper, esr-beta antikoerper, ESR2 antikoerper, ERBETA antikoerper, er antikoerper, ER-beta antikoerper, ER[b] antikoerper, Estrb antikoerper, ER[b]2 antikoerper, ER[b]a antikoerper, zfER[b]2 antikoerper, zfER-beta2 antikoerper, Erb2 antikoerper, esr2 antikoerper, erbeta antikoerper, Esr2 antikoerper, ERBeta2 antikoerper, estrogen receptor 2 antikoerper, estrogen receptor 2b antikoerper, estrogen receptor beta 2 antikoerper, estrogen receptor 2 (beta) antikoerper, estrogen receptor 2a antikoerper, estrogen receptor beta antikoerper, ESR2 antikoerper, esr2b antikoerper, erb2 antikoerper, esr2 antikoerper, Esr2 antikoerper, esr2a antikoerper, erbeta antikoerper
    Hintergrund
    ESR2 is a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized.
    Alias Symbols: Erb, ESRB, ESTRB, NR3A2, ER-BETA, ESR-BETA
    Protein Interaction Partner: PLSCR1, MEOX2, NOTCH2NL, RFX6, MMS19, BCAS2, NCOA1, RPS18, MRPS15, MRPS22, ZC3HAV1, PTCD3, EXOSC4, MRPS2, MED4, MRPS27, MRPS31, MED17, TRIM24, NRIP1, NCOA3, STAU1, SP1, PABPC5, MYLK2, RPS11, RPS4X, RPLP0, RPL36AL, PPP5C, HSPA8, ESR2, ESR1, ACTB, SRA1, ARI
    Protein Size: 530
    Molekulargewicht
    59 kDa
    Gen-ID
    2100
    NCBI Accession
    NM_001437, NP_001428
    UniProt
    Q92731
    Pathways
    Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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