WNT10B Antikörper (Middle Region)

Produktnummer ABIN2776702

Produktdetails anti-WNT10B Antikörper

Target: WNT10B (Wingless-Type MMTV Integration Site Family, Member 10B (WNT10B))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Hund, Pferd, Kaninchen, Meerschweinchen, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WNT10B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: GTSGSCQFKT CWRAAPEFRA VGAALRERLG RAIFIDTHNR NSGAFQPRLR

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against WNT10B. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human WNT10B

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 389 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu WNT10B

Target: WNT10B (Wingless-Type MMTV Integration Site Family, Member 10B (WNT10B))

Andere Bezeichnung: WNT10B (WNT10B Produkte)

Synonyme: WNT10B antikoerper, Xwnt-10b antikoerper, Xwnt10b antikoerper, wnt-12 antikoerper, Wnt12 antikoerper, SHFM6 antikoerper, WNT-12 antikoerper, Xwnt-10 antikoerper, wnt10 antikoerper, wnt10-A antikoerper, Zwnt[d] antikoerper, wnt10br antikoerper, wnt[d] antikoerper, Wnt family member 10B antikoerper, wingless-type MMTV integration site family, member 10B antikoerper, Wnt family member 10B S homeolog antikoerper, wingless-type MMTV integration site family, member 10b antikoerper, WNT10B antikoerper, wnt10b antikoerper, Wnt10b antikoerper, wnt10b.S antikoerper

Hintergrund: WNT10B is the ligand for members of the frizzled family of seven transmembrane receptors. WNT10B is a probable developmental protein. It may be a signaling molecule which affects the development of discrete regions of tissues. WNT10B is likely to signal over only few cell diameters.The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It may be involved in breast cancer, and its protein signaling is likely a molecular switch that governs adipogenesis. This protein is 96 % identical to the mouse Wnt10b protein at the amino acid level. This gene is clustered with another family member, WNT1, in the chromosome 12q13 region.
Alias Symbols: WNT-12, SHFM6
Protein Interaction Partner: UBC,
Protein Size: 389

Molekulargewicht: 40 kDa

Gen-ID: 7480

NCBI Accession: NM_003394, NP_003385

UniProt: O00744

Pathways: WNT Signalweg, Skeletal Muscle Fiber Development