EIF4E3 Antikörper (Middle Region)

Produktnummer ABIN2776663

Produktdetails anti-EIF4E3 Antikörper

Target: EIF4E3 (Eukaryotic Translation Initiation Factor 4E Family Member 3 (EIF4E3))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen, Zebrafisch (Danio rerio), Hund, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EIF4E3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: VQVWNVNASL VGEATVLEKI YELLPHITFK AVFYKPHEEH HAFEGGRGKH

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against EIF4E3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human EIF4E3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 224 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-EIF4E3 Antikörper (ABIN2776663)

Yi, Papadopoulos, Hagner, Wagner: "Hypoxia-inducible factor-1? (HIF-1?) promotes cap-dependent translation of selective mRNAs through up-regulating initiation factor eIF4E1 in breast cancer cells under hypoxia conditions." in: The Journal of biological chemistry, Vol. 288, Issue 26, pp. 18732-42, (2013) (PubMed).

Details zu EIF4E3

Target: EIF4E3 (Eukaryotic Translation Initiation Factor 4E Family Member 3 (EIF4E3))

Andere Bezeichnung: EIF4E3 (EIF4E3 Produkte)

Synonyme: eif4e3 antikoerper, wu:fc31f11 antikoerper, wu:fd15f11 antikoerper, zgc:92189 antikoerper, DDBDRAFT_0191035 antikoerper, DDBDRAFT_0234256 antikoerper, DDB_0191035 antikoerper, DDB_0234256 antikoerper, IF4E3 antikoerper, 1300018P11Rik antikoerper, AI451927 antikoerper, eIF4E-3 antikoerper, eukaryotic translation initiation factor 4E family member 3 antikoerper, eukaryotic translation initiation factor 4E family member 3 L homeolog antikoerper, eukaryotic translation initiation factor 4E member 3 antikoerper, eukaryotic translation initiation factor 4E family member 3 S homeolog antikoerper, EIF4E3 antikoerper, Eif4e3 antikoerper, eif4e3.L antikoerper, eif4e3 antikoerper, eIF4e3 antikoerper, eif4e3.S antikoerper

Hintergrund: EIF4E3 belongs to the EIF4E family of translational initiation factors that interact with the 5-prime cap structure of mRNA and recruit mRNA to the ribosome.
Alias Symbols: MGC39820, MGC86971
Protein Interaction Partner: ELAVL1, DCC,
Protein Size: 224

Molekulargewicht: 24 kDa

Gen-ID: 317649

NCBI Accession: NM_001134649, NP_001128123

UniProt: Q8N5X7