SRSF10 Antikörper (serine/arginine-Rich Splicing Factor 10) (C-Term)

Details for Product anti-SRSF10 Antibody No. ABIN2776611, Anbieter: Anmelden zum Anzeigen
Antigen
  • FUSIP1
  • SFRS13A
  • FUSIP2
  • NSSR
  • SFRS13
  • SRp38
  • SRrp40
  • TASR
  • TASR1
  • TASR2
  • Fusip1
  • NSSR1
  • NSSR2
  • Nssr
  • Sfrs13a
  • Srsf13a
  • fusip1
  • fusip2
  • nssr
  • sfrs13
  • sfrs13a
  • srp38
  • srrp40
  • tasr
  • tasr1
  • tasr2
  • serine and arginine rich splicing factor 10
  • serine/arginine-rich splicing factor 10
  • serine/arginine-rich splicing factor 10 S homeolog
  • SRSF10
  • Srsf10
  • srsf10.S
Epitop
C-Term
14
13
10
4
4
4
3
3
2
2
1
1
1
Reaktivität
Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus)
69
31
21
5
4
4
3
3
3
2
1
1
Wirt
Kaninchen
56
13
Klonalität
Polyklonal
Konjugat
Dieser SRSF10 Antikörper ist unkonjugiert
5
4
4
3
3
3
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunohistochemistry (IHC), Western Blotting (WB)
52
27
13
12
10
10
9
2
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human FUSIP1
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN977144.
Sequenz TDSKTHYKSG SRYEKESRKK EPPRSKSQSR SQSRSRSKSR SRSWTSPKSS
Homologie Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
Produktmerkmale This is a rabbit polyclonal antibody against FUSIP1. It was validated on Western Blot and immunohistochemistry.
Reinigung Affinity Purified
Andere Bezeichnung FUSIP1 (SRSF10 Antibody Abstract)
Hintergrund FUSIP1 is a member of the serine-arginine (SR) family of proteins, which is involved in constitutive and regulated RNA splicing. Members of this family are characterized by N-terminal RNP1 and RNP2 motifs, which are required for binding to RNA, and multiple C-terminal SR/RS repeats, which are important in mediating association with other cellular proteins. This protein can influence splice site selection of adenovirus E1A pre-mRNA. It interacts with the oncoprotein TLS, and abrogates the influence of TLS on E1A pre-mRNA splicing.This gene product is a member of the serine-arginine (SR) family of proteins, which is involved in constitutive and regulated RNA splicing. Members of this family are characterized by N-terminal RNP1 and RNP2 motifs, which are required for binding to RNA, and multiple C-terminal SR/RS repeats, which are important in mediating association with other cellular proteins. This protein can influence splice site selection of adenovirus E1A pre-mRNA. It interacts with the oncoprotein TLS, and abrogates the influence of TLS on E1A pre-mRNA splicing. Alternative splicing of this gene results in at least two transcript variants encoding different isoforms. In addition, transcript variants utilizing alternative polyA sites exist.
Alias Symbols: FUSIP2, NSSR, SFRS13, SRp38, SRrp40, TASR, TASR1, TASR2, FUSIP1, SFRS13A
Protein Interaction Partner: STAU1, WWOX, SUZ12, EED, RNF2, EZH2, HECW2, TRA2B, SRSF4, SRSF1, CSNK2A1, EIF4A3, MAGOH, PAXIP1, BARD1, SAP18, VTN, TCOF1, SRSF6, S100A9, PRKDC, NHP2L1, NFIA, SEPT2, MSH2, IK, EPRS, DHX15, BCAS2, TRIM55, THOC6, ZNF687, SMU1, TRMT112, TRA2A, PHGDH, NCSTN,
Protein Size: 262
Molekulargewicht 29 kDa
Gen-ID 10772
NCBI Accession NM_054016, NP_473357
UniProt O75494
Pathways Ribonucleoprotein Complex Subunit Organization
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 262 AA

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Bilder des Herstellers
Western Blotting (WB) image for anti-serine/arginine-Rich Splicing Factor 10 (SRSF10) (C-Term) antibody (ABIN2776611) WB Suggested Anti-FUSIP1 Antibody Titration: 0.2-1 ug/ml
Positive Contro...
Immunohistochemistry (IHC) image for anti-serine/arginine-Rich Splicing Factor 10 (SRSF10) (C-Term) antibody (ABIN2776611) anti-serine/arginine-Rich Splicing Factor 10 (SRSF10) (C-Term) antibody (Image 2)
Western Blotting (WB) image for anti-serine/arginine-Rich Splicing Factor 10 (SRSF10) (C-Term) antibody (ABIN2776611) WB Suggested Anti-FUSIP1
Antibody Titration: 0.2-1 µg/mL
Positive Contr...
Allgemeine Veröffentlichungen Shin, Kleiman, Manley: "Multiple properties of the splicing repressor SRp38 distinguish it from typical SR proteins." in: Molecular and cellular biology, Vol. 25, Issue 18, pp. 8334-43, 2005 (PubMed).

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