FIP1L1 Antikörper (C-Term)

Produktnummer ABIN2776582

Produktdetails anti-FIP1L1 Antikörper

Target: FIP1L1 (FIP1 Like 1 (FIP1L1))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Hund, Meerschweinchen, Zebrafisch (Danio rerio), Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FIP1L1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: EYAERGYERH RASREKEERH RERRHREKEE TRHKSSRSNS RRRHESEEGD

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against FIP1L1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human FIP1L1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 594 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu FIP1L1

Target: FIP1L1 (FIP1 Like 1 (FIP1L1))

Andere Bezeichnung: FIP1L1 (FIP1L1 Produkte)

Synonyme: FIP1 antikoerper, Rhe antikoerper, hFip1 antikoerper, 1300019H17Rik antikoerper, Rje antikoerper, fip1l1 antikoerper, wu:fd36f11 antikoerper, zgc:103421 antikoerper, factor interacting with PAPOLA and CPSF1 antikoerper, factor interacting with PAPOLA and CPSF1 S homeolog antikoerper, FIP1 like 1 (S. cerevisiae) antikoerper, FIP1 like 1b (S. cerevisiae) antikoerper, fip1l1 antikoerper, FIP1L1 antikoerper, fip1l1.S antikoerper, Fip1l1 antikoerper, fip1l1b antikoerper

Hintergrund: FIP1L1 is a component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. FIP1L1 contributes to poly(A) site recognition and stimulates poly(A) addition. It binds to U-rich RNA sequence elements surrounding the poly(A) site. FIP1L1 may act to tether poly(A) polymerase to the CPSF complex.
Alias Symbols: DKFZp586K0717, FLJ33619, Rhe, hFip1
Protein Interaction Partner: ZMYND19, CPSF4, NAA10, SGTA, GOLGA2, STAU1, UBC, WWOX, SUZ12, RNF2, EZH2, PRMT6, PRMT2, CLK2, HDAC9, CSNK2A1, LIG4, WDR33, CPSF2, CPSF3, CPSF1, NUP153, APP, COPS5, HNRNPA1, SRRM2, RNPS1,
Protein Size: 594

Molekulargewicht: 65 kDa

Gen-ID: 81608

NCBI Accession: NM_030917, NP_112179

UniProt: Q6UN15