SMPD1 Antikörper (Middle Region)

Produktnummer ABIN2776372

Produktdetails anti-SMPD1 Antikörper

Target: SMPD1 (Sphingomyelin phosphodiesterase 1, Acid Lysosomal (SMPD1))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Schaf, Hund, Pferd, Kaninchen, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SMPD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: RLRDVFGWGN LTCPICKGLF TAINLGLKKE PNVARVGSVA IKLCNLLKIA

Homologie: Cow: 83%, Dog: 87%, Guinea Pig: 87%, Horse: 80%, Human: 100%, Mouse: 80%, Rabbit: 87%, Rat: 87%, Sheep: 83%

Produktmerkmale: This is a rabbit polyclonal antibody against SMPD1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SMPD1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SMPD1

Target: SMPD1 (Sphingomyelin phosphodiesterase 1, Acid Lysosomal (SMPD1))

Andere Bezeichnung: SMPD1 (SMPD1 Produkte)

Synonyme: ASM antikoerper, ASMASE antikoerper, NPD antikoerper, A-SMase antikoerper, Zn-SMase antikoerper, aSMase antikoerper, SMPD1 antikoerper, sphingomyelin phosphodiesterase 1 antikoerper, sphingomyelin phosphodiesterase 1, acid lysosomal antikoerper, sphingomyelin phosphodiesterase antikoerper, SMPD1 antikoerper, Smpd1 antikoerper, LOC5578088 antikoerper

Hintergrund: The protein encoded by this gene is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB). Multiple transcript variants encoding different isoforms have been identified.
Alias Symbols: ASM, NPD, ASMASE
Protein Size: 171

Molekulargewicht: 18 kDa

Gen-ID: 6609

NCBI Accession: NM_000543, NP_000534

UniProt: P17405