Kv3.4 Antikörper (Middle Region)

Produktnummer ABIN2776170

Produktdetails anti-Kv3.4 Antikörper

Target: Kv3.4 (KCNC4) (Potassium Voltage-Gated Channel, Shaw-Related Subfamily, Member 4 (KCNC4))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Pferd, Rind (Kuh), Hund, Kaninchen, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Kv3.4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: NIDRNVTEIL RVGNITSVHF RREVETEPIL TYIEGVCVLW FTLEFLVRIV

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against KCNC4. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human KCNC4

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 582 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Kv3.4

Target: Kv3.4 (KCNC4) (Potassium Voltage-Gated Channel, Shaw-Related Subfamily, Member 4 (KCNC4))

Andere Bezeichnung: KCNC4 (KCNC4 Produkte)

Synonyme: C1orf30 antikoerper, HKSHIIIC antikoerper, KSHIIIC antikoerper, KV3.4 antikoerper, AI850292 antikoerper, Kcr2-4 antikoerper, Kv3.4 antikoerper, potassium voltage-gated channel subfamily C member 4 antikoerper, potassium channel, voltage gated Shaw related subfamily C, member 4 antikoerper, potassium voltage gated channel, Shaw-related subfamily, member 4 antikoerper, KCNC4 antikoerper, kcnc4 antikoerper, Kcnc4 antikoerper

Hintergrund: KCNC4 is part of the Shaker gene family of Drosophila. It encodes components of voltage-gated potassium channels and is comprised of four subfamilies. Based on sequence similarity, this gene is similar to the Shaw subfamily. KCNC4 belongs to the delayed rectifier class of channel proteins and is an integral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes. It generates atypical voltage-dependent transient current that may be important for neuronal excitability. Several transcript variants encoding different isoforms have been found for this gene.The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and is comprised of four subfamilies. Based on sequence similarity, this gene is similar to the Shaw subfamily. The protein encoded by this gene belongs to the delayed rectifier class of channel proteins and is an integral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes. It generates atypical voltage-dependent transient current that may be important for neuronal excitability. Several transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: HKSHIIIC, KSHIIIC, KV3.4, MGC126818, C1orf30
Protein Size: 582

Molekulargewicht: 64 kDa

Gen-ID: 3749

NCBI Accession: NM_153763, NP_720198