SCN7A Antikörper (N-Term)

Produktnummer ABIN2776152

Produktdetails anti-SCN7A Antikörper

Target: SCN7A (Sodium Channel, Voltage-Gated, Type VII, alpha Subunit (SCN7A))

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte, Maus, Hund, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SCN7A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: PFIYGNLSQG MVSEPLEDVD PYYYKKKNTF IVLNKNRTIF RFNAASILCT

Homologie: Dog: 79%, Guinea Pig: 80%, Human: 100%, Mouse: 79%, Rat: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against SCN7A. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of human SCN7A

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SCN7A

Target: SCN7A (Sodium Channel, Voltage-Gated, Type VII, alpha Subunit (SCN7A))

Andere Bezeichnung: SCN7A (SCN7A Produkte)

Synonyme: 1110034K09Rik antikoerper, AI642000 antikoerper, NaG antikoerper, Nav2 antikoerper, Nav2.3 antikoerper, Nax antikoerper, Scn6a antikoerper, Na-G antikoerper, Nav2.1 antikoerper, Nav2.2 antikoerper, SCN6A antikoerper, sodium channel, voltage-gated, type VII, alpha antikoerper, sodium voltage-gated channel alpha subunit 7 antikoerper, Scn7a antikoerper, SCN7A antikoerper

Hintergrund: This gene encodes one of the many voltage-gated sodium channel proteins. For proper functioning of neurons and muscles during action potentials, voltage-gated sodium channels direct sodium ion diffusion for membrane depolarization. This sodium channel protein has some atypical characteristics, the similarity between the human and mouse proteins is lower compared to other orthologous sodium channel pairs. Also, the S4 segments, which sense voltage changes, have fewer positive charged residues that in other sodium channels, domain 4 has fewer arginine and lysine residues compared to other sodium channel proteins. Several alternatively spliced transcript variants exist, but the full-length natures of all of them remain unknown.
Alias Symbols: NaG, SCN6A, Nav2.1, Nav2.2
Protein Size: 762

Molekulargewicht: 83 kDa

Gen-ID: 6332

NCBI Accession: NM_002976, NP_002967

UniProt: Q01118