KCNN1 Antikörper (C-Term)

Produktnummer ABIN2776145

Produktdetails anti-KCNN1 Antikörper

Target: KCNN1 (Potassium Intermediate/small Conductance Calcium-Activated Channel, Subfamily N, Member 1 (KCNN1))

Bindungsspezifität: C-Term

Reaktivität: Human, Ratte, Meerschweinchen, Schwein, Rind (Kuh), Hund, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KCNN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: KIEQGKLNDQ ANTLTDLAKT QTVMYDLVSE LHAQHEELEA RLATLESRLD

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 79%, Horse: 92%, Human: 100%, Pig: 93%, Rat: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against KCNN1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human KCNN1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 543 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-KCNN1 Antikörper (ABIN2776145)

Arnold, Mühlen: "The influence of the thickness of non-piezoelectric pieces on pre-stressed piezotransducers." in: Ultrasonics, Vol. 41, Issue 3, pp. 191-6, (2003) (PubMed).

Details zu KCNN1

Target: KCNN1 (Potassium Intermediate/small Conductance Calcium-Activated Channel, Subfamily N, Member 1 (KCNN1))

Andere Bezeichnung: KCNN1 (KCNN1 Produkte)

Synonyme: KCNN1 antikoerper, kcnn1 antikoerper, si:ch211-200a16.1 antikoerper, sk1 antikoerper, hsk1 antikoerper, skca1 antikoerper, MGC145919 antikoerper, KCa2.1 antikoerper, SK1 antikoerper, SKCA1 antikoerper, hSK1 antikoerper, AI854248 antikoerper, potassium calcium-activated channel subfamily N member 1 antikoerper, potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1b antikoerper, potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 antikoerper, small conductance calcium-activated potassium channel protein 1 antikoerper, potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1 antikoerper, KCNN1 antikoerper, kcnn1b antikoerper, kcnn1 antikoerper, LOC100456154 antikoerper, Kcnn1 antikoerper

Hintergrund: Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. KCNN1 is a member of the KCNN family of potassium channels.
Alias Symbols: SK1, hSK1, SKCA1, KCa2.1
Protein Interaction Partner: UBC,
Protein Size: 543

Molekulargewicht: 60 kDa

Gen-ID: 3780

NCBI Accession: NM_002248, NP_002239

UniProt: Q6DJU4