GABRB1 Antikörper (N-Term)

Produktnummer ABIN2776114

Produktdetails anti-GABRB1 Antikörper

Target: GABRB1 (gamma-aminobutyric Acid (GABA) A Receptor, Subunit beta 1 (GABRB1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Kaninchen, Hund, Meerschweinchen, Zebrafisch (Danio rerio), Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GABRB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: TLDNRVADQL WVPDTYFLND KKSFVHGVTV KNRMIRLHPD GTVLYGLRIT

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against GABRB1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GABRB1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 474 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu GABRB1

Target: GABRB1 (gamma-aminobutyric Acid (GABA) A Receptor, Subunit beta 1 (GABRB1))

Andere Bezeichnung: GABRB1 (GABRB1 Produkte)

Synonyme: AW061132 antikoerper, B230208N19Rik antikoerper, Gabrb-1 antikoerper, GARB1 antikoerper, si:dkey-20i10.4 antikoerper, gamma-aminobutyric acid type A receptor beta1 subunit antikoerper, gamma-aminobutyric acid (GABA) A receptor, subunit beta 1 antikoerper, gamma-aminobutyric acid type A receptor beta 1 subunit antikoerper, gamma-aminobutyric acid (GABA) A receptor, beta 1 antikoerper, GABRB1 antikoerper, Gabrb1 antikoerper, gabrb1 antikoerper

Hintergrund: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, beta 1 subunit. It is mapped to chromosome 4p12 in a cluster comprised of genes encoding alpha 4, alpha 2 and gamma 1 subunits of the GABA A receptor. Alteration of this gene is implicated in the pathogenetics of schizophrenia. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: -
Protein Interaction Partner: HSPA8, NEUROD4, NOD1, UBC, CUL1, UBQLN1, ARFGEF2, AKAP5, C1QBP, PIK3CA,
Protein Size: 474

Molekulargewicht: 51 kDa

Gen-ID: 2560

NCBI Accession: NM_000812, NP_000803

UniProt: P18505