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CAND1 Antikörper (Middle Region)

CAND1 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Hund, Pferd, Kaninchen, Zebrafisch (Danio rerio) WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2775887
  • Target Alle CAND1 Antikörper anzeigen
    CAND1 (Cullin-Associated and Neddylation-Dissociated 1 (CAND1))
    Bindungsspezifität
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    • 22
    • 11
    • 8
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Hund, Pferd, Kaninchen, Zebrafisch (Danio rerio)
    Wirt
    • 17
    • 5
    Kaninchen
    Klonalität
    • 18
    • 4
    Polyklonal
    Konjugat
    • 19
    • 1
    • 1
    • 1
    Dieser CAND1 Antikörper ist unkonjugiert
    Applikation
    • 15
    • 10
    • 6
    • 5
    • 4
    • 3
    • 1
    Western Blotting (WB)
    Sequenz
    AALLTIPEAE KSPLMSEFQS QISSNPELAA IFESIQKDSS STNLESMDTS
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
    Produktmerkmale
    This is a rabbit polyclonal antibody against CAND1. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human CAND1
    Top Product
    Discover our top product CAND1 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 1230 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    CAND1 (Cullin-Associated and Neddylation-Dissociated 1 (CAND1))
    Andere Bezeichnung
    CAND1 (CAND1 Produkte)
    Synonyme
    TIP120 antikoerper, TIP120A antikoerper, ATCAND1 antikoerper, CULLIN-ASSOCIATED AND NEDDYLATION DISSOCIATED 1 antikoerper, ETA2 antikoerper, HEMIVENATA antikoerper, HVE antikoerper, T8K22.14 antikoerper, T8K22_14 antikoerper, cullin-associated and neddylation dissociated antikoerper, Tip120 antikoerper, Tip120A antikoerper, fb78a05 antikoerper, wu:fb78a05 antikoerper, zgc:55729 antikoerper, tip120 antikoerper, tip120a antikoerper, cand2 antikoerper, 2310038O07Rik antikoerper, 6330512O03Rik antikoerper, AI195005 antikoerper, AI846556 antikoerper, D10Ertd516e antikoerper, Tp120a antikoerper, mKIAA0829 antikoerper, cullin associated and neddylation dissociated 1 antikoerper, cullin-associated and neddylation dissociated antikoerper, cullin-associated and neddylation-dissociated 1 antikoerper, cullin-associated and neddylation-dissociated 1 L homeolog antikoerper, cullin-associated NEDD8-dissociated protein 1 antikoerper, cullin associated and neddylation disassociated 1 antikoerper, CAND1 antikoerper, Cand1 antikoerper, cand1 antikoerper, cand1.L antikoerper, LOC100159824 antikoerper, LOC100177977 antikoerper
    Hintergrund
    CAND1 enhances transcription from various types of promoters. It is a regulatory protein that interferes with the assembly of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex and thereby down-regulates ubiquitination of target proteins. CAND1 prevents neddylation of CUL1 by physically blocking access to the neddylation site. CAND1 disrupts interactions between CUL1 and SKP1A and between CUL1 and F-box proteins.
    Alias Symbols: DKFZp434M1414, FLJ10114, FLJ10929, FLJ38691, FLJ90441, KIAA0829, TIP120, TIP120A
    Protein Interaction Partner: ISG15, SUMO2, SUMO3, UBE2D1, UBC, UBE2M, CUL1, ASB2, ASB1, PPM1G, PAWR, OSBP, KARS, GARS, CARS, APEH, STAT1, SHMT2, IPO7, SEC23A, JMJD6, HSPA4, TRMT112, ZYX, DCUN1D5, DCUN1D1, SRPK2, UBD, FBXL3, FN1, CFTR, vif, CA9, ECT2, NOTCH1, CUL4A, CUL5, RBX1, ERCC6,
    Protein Size: 1230
    Molekulargewicht
    136 kDa
    Gen-ID
    55832
    NCBI Accession
    NM_018448, NP_060918
    UniProt
    Q86VP6
    Pathways
    Regulation of Actin Filament Polymerization
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