ATG4B Antikörper (ATG4 Autophagy Related 4 Homolog B (S. Cerevisiae)) (C-Term)

Details for Product anti-ATG4B Antibody No. ABIN2775793, Anbieter: Anmelden zum Anzeigen
Antigen
  • apg4b
  • APG4B
  • AUTL1
  • 2510009N07Rik
  • AW048066
  • Apg4b
  • Atg4bl
  • Autl1
  • Aut2b2
  • autophagy related 4B cysteine peptidase
  • autophagy-related 4b
  • Peptidase family C54 protein
  • cysteine protease ATG4B
  • ATG4 autophagy related 4 homolog B (S. cerevisiae)
  • autophagy related 4B, cysteine peptidase
  • autophagy related 4B, cysteine peptidase L homeolog
  • ATG4B
  • Atg4b
  • AT3G59950
  • Tsp_08582
  • Tsp_11599
  • atg4b
  • atg4b.L
Epitop
C-Term
48
22
18
18
16
15
12
10
9
9
7
5
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus), Zebrafisch (Danio rerio)
176
100
46
11
9
7
7
7
6
5
5
4
4
3
2
1
1
Wirt
Kaninchen
171
7
1
Klonalität
Polyklonal
Konjugat
Dieser ATG4B Antikörper ist unkonjugiert
7
7
7
6
6
6
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunohistochemistry (IHC), Western Blotting (WB)
155
50
43
42
38
27
13
2
2
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human APG4B
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN973302.
Sequenz LGGALPMFEL VELQPSHLAC PDVLNLSLDS SDVERLERFF DSEDEDFEIL
Homologie Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%
Produktmerkmale This is a rabbit polyclonal antibody against APG4B. It was validated on Western Blot and immunohistochemistry.
Reinigung Affinity Purified
Andere Bezeichnung APG4B (ATG4B Antibody Abstract)
Hintergrund Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. APG4B encodes a member of the autophagin protein family and is also designated as a member of the C-54 family of cysteine proteases.
Alias Symbols: APG4B, AUTL1
Protein Interaction Partner: SUMO2, MAP1LC3B, MAP1LC3A, BAG3, ATG8, YWHAB, GABARAPL1, SQSTM1, UBC, GABARAPL2, ATG10, ATG3, AMBRA1, GABARAP, CAMKK2, ATG12, ULK1, STK3, KRT4, ANXA1, FBXW11, LINC00341,
Protein Size: 393
Molekulargewicht 44 kDa
Gen-ID 23192
NCBI Accession NM_013325, NP_037457
UniProt Q9Y4P1
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 393 AA

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Bilder des Herstellers
Western Blotting (WB) image for anti-ATG4 Autophagy Related 4 Homolog B (S. Cerevisiae) (ATG4B) (C-Term) antibody (ABIN2775793) WB Suggested Anti-APG4B Antibody Titration: 0.2-1 ug/ml
ELISA Titer:
Immunohistochemistry (IHC) image for anti-ATG4 Autophagy Related 4 Homolog B (S. Cerevisiae) (ATG4B) (C-Term) antibody (ABIN2775793) anti-ATG4 Autophagy Related 4 Homolog B (S. Cerevisiae) (ATG4B) (C-Term) antibody (Image 2)
Allgemeine Veröffentlichungen Tanida, Sou, Ezaki, Minematsu-Ikeguchi, Ueno, Kominami: "HsAtg4B/HsApg4B/autophagin-1 cleaves the carboxyl termini of three human Atg8 homologues and delipidates microtubule-associated protein light chain 3- and GABAA receptor-associated protein-phospholipid conjugates." in: The Journal of biological chemistry, Vol. 279, Issue 35, pp. 36268-76, 2004 (PubMed).

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