MARCH4 Antikörper (N-Term)
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- Target Alle MARCH4 Antikörper anzeigen
- MARCH4 (Membrane-Associated Ring Finger (C3HC4) 4, E3 Ubiquitin Protein Ligase (MARCH4))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte, Hund, Pferd, Meerschweinchen, Kaninchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser MARCH4 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- GLLKCRCRML FNDLKVFLLR RPPQAPLPMH GDPQPPGLAA NNTLPALGAG
- Homologie
- Dog: 92%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 85%, Rabbit: 85%, Rat: 92%
- Produktmerkmale
- This is a rabbit polyclonal antibody against MARCH4. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human MARCH4
- Top Product
- Discover our top product MARCH4 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 410 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- MARCH4 (Membrane-Associated Ring Finger (C3HC4) 4, E3 Ubiquitin Protein Ligase (MARCH4))
- Andere Bezeichnung
- MARCH4 (MARCH4 Produkte)
- Synonyme
- MARCH-IV antikoerper, RNF174 antikoerper, BC056494 antikoerper, mKIAA1399 antikoerper, MARCH4 antikoerper, si:ch211-239d11.2 antikoerper, membrane associated ring-CH-type finger 4 antikoerper, membrane-associated ring finger (C3HC4) 4 antikoerper, MARCH4 antikoerper, March4 antikoerper, march4 antikoerper
- Hintergrund
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MARCH4 is an E3 ubiquitin-protein ligase that may mediate ubiquitination of MHC-I and CD4, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
Alias Symbols: MARCH-IV, MGC104908, RNF174
Protein Interaction Partner: UBE2H, UBE2D1, ULBP1, CD4,
Protein Size: 410 - Molekulargewicht
- 45 kDa
- Gen-ID
- 57574
- NCBI Accession
- NM_020814, NP_065865
- UniProt
- Q9P2E8
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