RAD18 Antikörper (Middle Region)
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- Target Alle RAD18 Antikörper anzeigen
- RAD18 (E3 ubiquitin-protein ligase RAD18 (RAD18))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Ratte, Maus, Kaninchen, Rind (Kuh), Hund, Pferd, Meerschweinchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser RAD18 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- LSDRDLKKKL KEHGLSIQGN KQQLIKRHQE FVHMYNAQCD ALHPKSAAEI
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against RAD18. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human RAD18
- Top Product
- Discover our top product RAD18 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 495 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- RAD18 (E3 ubiquitin-protein ligase RAD18 (RAD18))
- Andere Bezeichnung
- RAD18 (RAD18 Produkte)
- Synonyme
- RNF73 antikoerper, 2810024C04Rik antikoerper, Rad18sc antikoerper, zgc:55577 antikoerper, RAD18 antikoerper, DDBDRAFT_0218120 antikoerper, DDBDRAFT_0304878 antikoerper, DDB_0218120 antikoerper, DDB_0304878 antikoerper, DKFZp469H0810 antikoerper, RAD18, E3 ubiquitin protein ligase antikoerper, RAD18 E3 ubiquitin protein ligase antikoerper, E3 ubiquitin-protein ligase RAD18 antikoerper, E3 ubiquitin-protein ligase antikoerper, DNA repair protein and ATPase antikoerper, C3HC4-type zinc finger-containing protein antikoerper, RAD18 antikoerper, Rad18 antikoerper, rad18 antikoerper
- Hintergrund
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RAD18 is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, RAD18 is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens.
Alias Symbols: RNF73
Protein Interaction Partner: TAX1BP1, UBC, SHPRH, RAD18, SIVA1, USP2, UBE2B, UBE2A, HLTF, PCNA, BPLF1, USP5, DBF4, BRCA1, DZIP3, POLH, DTL, Ankrd32, MLKL, ECT2, RPL10A, TRIM23, PCGF6, TRIM8, RFC2, CPD, SPRTN, ZMYM2, MAPK8, POLN, WRNIP1, gag-pol, ORC2, SUMO2, POLK, NBN, Smc6, HIST1H2A
Protein Size: 495 - Molekulargewicht
- 56 kDa
- Gen-ID
- 56852
- NCBI Accession
- NM_020165, NP_064550
- UniProt
- Q9NS91
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