DACT1 Antikörper (Middle Region)

Produktnummer ABIN2774363

Produktdetails anti-DACT1 Antikörper

Target: DACT1 (Dapper, Antagonist of beta-Catenin, Homolog 1 (DACT1))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio), Meerschweinchen, Kaninchen, Rind (Kuh), Hund, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DACT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: LSLVQKKTHP VRTNKPRTSV NADPTKGLLR NGSVCVRAPG GVSQGNSVNL

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 92%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 92%, Rat: 100%, Zebrafish: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against DACT1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 836 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu DACT1

Target: DACT1 (Dapper, Antagonist of beta-Catenin, Homolog 1 (DACT1))

Andere Bezeichnung: DACT1 (DACT1 Produkte)

Synonyme: XDpr antikoerper, dpr1 antikoerper, frodo antikoerper, hdpr1 antikoerper, Dapper antikoerper, thyex3 antikoerper, dapper1 antikoerper, MGC89695 antikoerper, frd1 antikoerper, frodo1 antikoerper, 4921528D17Rik antikoerper, AI115603 antikoerper, DAPPER antikoerper, DAPPER1 antikoerper, FRODO antikoerper, Frd1 antikoerper, Frodo1 antikoerper, MDpr1 antikoerper, MTNG3 antikoerper, THYEX3 antikoerper, DPR1 antikoerper, HDPR1 antikoerper, DACT1 antikoerper, RGD1564008 antikoerper, XDpr1a antikoerper, dact1 antikoerper, dpr antikoerper, XDpr1b antikoerper, dishevelled-binding antagonist of beta-catenin 1 antikoerper, dishevelled binding antagonist of beta catenin 1 antikoerper, dishevelled-binding antagonist of beta-catenin 1 L homeolog antikoerper, dishevelled-binding antagonist of beta-catenin 1 S homeolog antikoerper, dact1 antikoerper, Dact1 antikoerper, DACT1 antikoerper, dact1.L antikoerper, dact1.S antikoerper

Hintergrund: DACT1 positively regulates DVL2-mediated signaling pathways during development. It binds to DVL2 and impedes the degradation of CTNNB1/beta-catenin, thereby enhancing the transcriptional activation of target genes of the Wnt signaling pathway.
Alias Symbols: DAPPER, DAPPER1, DPR1, FRODO, HDPR1, THYEX3
Protein Interaction Partner: BECN1, PIK3C3, ATG14, CBX6, PPP1CC, Dact1, Dact3, C7orf25, TK1, SH3GL2, CSNK2B, LEF1, HDAC1,
Protein Size: 836

Molekulargewicht: 92 kDa

Gen-ID: 51339

NCBI Accession: NM_016651, NP_057735

UniProt: Q9NYF0

Pathways: Positive Regulation of fat Cell Differentiation