VPS4B Antikörper (N-Term)
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- Target Alle VPS4B (vps4b) Antikörper anzeigen
- VPS4B (vps4b) (Vacuolar Protein Sorting 4 Homolog B (vps4b))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Ratte, Hund, Meerschweinchen, Pferd, Kaninchen, Rind (Kuh)
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser VPS4B Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- EKLKEYLKNK EKKAQKPVKE GQPSPADEKG NDSDGEGESD DPEKKKLQNQ
- Homologie
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Rabbit: 86%, Rat: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against VPS4B. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Top Product
- Discover our top product vps4b Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 444 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- VPS4B (vps4b) (Vacuolar Protein Sorting 4 Homolog B (vps4b))
- Andere Bezeichnung
- VPS4B (vps4b Produkte)
- Synonyme
- zgc:63682 antikoerper, vps4a antikoerper, SKD1 antikoerper, SKD1B antikoerper, VPS4-2 antikoerper, 8030489C12Rik antikoerper, Skd1 antikoerper, vacuolar protein sorting 4 homolog B antikoerper, vacuolar protein sorting 4 homolog B S homeolog antikoerper, vacuolar protein sorting 4b homolog B (S. cerevisiae) antikoerper, vacuolar protein sorting 4 homolog B (S. cerevisiae) antikoerper, vacuolar protein sorting 4B antikoerper, Vps4b antikoerper, vps4b.S antikoerper, vps4b antikoerper, VPS4B antikoerper
- Hintergrund
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The protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. Mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be a yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 18, the gene for the other resides on chromosome 16.
Alias Symbols: MIG1, SKD1, SKD1B, VPS4-2
Protein Interaction Partner: ZFYVE19, CHMP5, UBC, HTRA2, CHMP4A, TTLL12, AHCYL1, SSSCA1, YAP1, UBE4B, PDCD6IP, USP34, VPS26A, USP8, ZPR1, NUP214, TYMS, RAB5B, IGBP1, TTC9C, ZNF585B, UBQLN4, UBXN1, UBQLN1, CUL3, CHMP2A, CHMP1A, ELAVL1, BABAM1, CHMP1B, VPS4A, VPS4, LIP5,
Protein Size: 444 - Molekulargewicht
- 49 kDa
- Gen-ID
- 9525
- NCBI Accession
- NM_004869, NP_004860
- UniProt
- O75351
- Pathways
- Microtubule Dynamics, CXCR4-mediated Signaling Events
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