NFKBIZ Antikörper (C-Term)

Produktnummer ABIN2774196

Produktdetails anti-NFKBIZ Antikörper

Target: NFKBIZ (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, zeta (NFKBIZ))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen, Ziege, Meerschweinchen, Schaf, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NFKBIZ Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: VRLLMRKGAD PSTRNLENEQ PVHLVPDGPV GEQIRRILKG KSIQQRAPPY

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 91%

Produktmerkmale: This is a rabbit polyclonal antibody against Nfkbiz. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide corresponding to a region of Mouse

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 728 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu NFKBIZ

Target: NFKBIZ (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, zeta (NFKBIZ))

Andere Bezeichnung: Nfkbiz (NFKBIZ Produkte)

Synonyme: RGD1310834 antikoerper, NFKBIZ antikoerper, MAIL antikoerper, AA408868 antikoerper, INAP antikoerper, Mail antikoerper, IKBZ antikoerper, NFKB inhibitor zeta antikoerper, nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta antikoerper, nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta antikoerper, Nfkbiz antikoerper, NFKBIZ antikoerper, nfkbiz antikoerper

Hintergrund: Nfkbiz is involved in regulation of NF-kappa-B transcription factor complexes. It inhibits NF-kappa-B activity without affecting its nuclear translocation upon stimulation. It inhibits DNA-binding of RELA and NFKB1/p50, and of the NF-kappa-B p65-p50 heterodimer and the NF-kappa-B p50-p50 homodimer. It seems also to activate NF-kappa-B-mediated transcription. In vitro, upon association with NFKB1/p50, Nfkbiz has transcriptional activation activity and, together with NFKB1/p50 and RELA, Nfkbiz is recruited to LCN2 promoters.
Alias Symbols: AA408868, INAP, Mail
Protein Interaction Partner: Nfkb2, Nfkb1, Ikbkg, Elf5, Ehf, Il6,
Protein Size: 728

Molekulargewicht: 80 kDa

Gen-ID: 80859

NCBI Accession: NM_030612, NP_085115

UniProt: Q9EST8

Pathways: NF-kappaB Signalweg