APH1B Antikörper (C-Term)

Produktnummer ABIN2774063

Produktdetails anti-APH1B Antikörper

Target: APH1B (Aph1b) (Anterior Pharynx Defective 1 Homolog B (Aph1b))

Bindungsspezifität: C-Term

Reaktivität: Maus, Human, Ratte, Kaninchen, Rind (Kuh), Hund, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser APH1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: YYGINLASAF IILVLMGTWA FLAAGGSCRS LKLCLLCQDK NFLLYNQRSR

Homologie: Cow: 77%, Dog: 85%, Guinea Pig: 92%, Horse: 77%, Human: 100%, Mouse: 92%, Rabbit: 85%, Rat: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against APH1B. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 216 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu APH1B

Target: APH1B (Aph1b) (Anterior Pharynx Defective 1 Homolog B (Aph1b))

Andere Bezeichnung: APH1B (Aph1b Produkte)

Synonyme: APH-1B antikoerper, PRO1328 antikoerper, PSFL antikoerper, TAAV688 antikoerper, APH-1B' antikoerper, 2310057K14Rik antikoerper, Aph1c antikoerper, aph-1 homolog B, gamma-secretase subunit antikoerper, aph-1 homolog B, gamma secretase subunit antikoerper, aph1 homolog B, gamma secretase subunit antikoerper, APH1B antikoerper, Aph1b antikoerper

Hintergrund: This gene encodes a multi-pass transmembrane protein that is a functional component of the gamma-secretase complex, which also contains presenilin and nicastrin. This protein represents a stabilizing cofactor for the presenilin holoprotein in the complex. The gamma-secretase complex catalyzes the cleavage of integral proteins such as notch receptors and beta-amyloid precursor protein.
Alias Symbols: APH-1B, DKFZp564D0372, FLJ33115, PRO1328, PSFL, TAAV688
Protein Interaction Partner: UBC, PSENEN, NCSTN, PSEN2, PSEN1,
Protein Size: 216

Molekulargewicht: 23 kDa

Gen-ID: 83464

NCBI Accession: NM_001145646, NP_001139118

UniProt: Q564N3

Pathways: Notch Signalweg, Neurotrophin Signalübertragung