ATP6V0C Antikörper (Middle Region)

Produktnummer ABIN2773857

Produktdetails anti-ATP6V0C Antikörper

Target: ATP6V0C (ATPase, H+ Transporting, Lysosomal 16kDa, V0 Subunit C (ATP6V0C))

Bindungsspezifität: Middle Region

Reaktivität: Human, Ratte, Rind (Kuh), Hund, Pferd, Schwein, Kaninchen, Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATP6V0C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: VVAVLIANSL NDDISLYKSF LQLGAGLSVG LSGLAAGFAI GIVGDAGVRG

Homologie: Cow: 86%, Dog: 86%, Horse: 93%, Human: 100%, Pig: 79%, Rabbit: 86%, Rat: 90%, Sheep: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against ATP6V0C. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ATP6V0C

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 155 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ATP6V0C

Target: ATP6V0C (ATPase, H+ Transporting, Lysosomal 16kDa, V0 Subunit C (ATP6V0C))

Andere Bezeichnung: ATP6V0C (ATP6V0C Produkte)

Synonyme: ATP6C antikoerper, ATP6L antikoerper, ATPL antikoerper, VATL antikoerper, VPPC antikoerper, Vma3 antikoerper, Atp6c antikoerper, Atp6c2 antikoerper, Atp6l antikoerper, Atpl antikoerper, Atpl-rs1 antikoerper, PL16 antikoerper, CHUNP6904 antikoerper, atp6l antikoerper, atp6v0c antikoerper, cb993 antikoerper, fb57d09 antikoerper, wu:fb57d09 antikoerper, atp6c antikoerper, atpl antikoerper, ductin antikoerper, vatl antikoerper, vma3 antikoerper, PLP antikoerper, wu:fc74d11 antikoerper, zgc:111904 antikoerper, zgc:77708 antikoerper, ATPase H+ transporting V0 subunit c antikoerper, ATPase, H+ transporting, lysosomal V0 subunit C antikoerper, ATPase H+ transporting V0 subunit C antikoerper, ATPase, H+ transporting, lysosomal, V0 subunit ca antikoerper, ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c antikoerper, ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c L homeolog antikoerper, V-type proton ATPase 16 kDa proteolipid subunit antikoerper, ATPase, H+ transporting, lysosomal, V0 subunit cb antikoerper, ATP6V0C antikoerper, Atp6v0c antikoerper, atp6v0ca antikoerper, atp6v0c antikoerper, atp6v0c.L antikoerper, LOC696755 antikoerper, atp6v0cb antikoerper

Hintergrund: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is part of the V0 domain. This gene had the previous symbols of ATP6C and ATP6L.
Alias Symbols: ATP6C, ATP6L, ATPL, VATL, Vma3, VPPC
Protein Interaction Partner: SMIM3, UBC, PSMA3, MSR1, EDA, CERS2, CLIC1, RNF182, MARK3, ARF6,
Protein Size: 155

Molekulargewicht: 16 kDa

Gen-ID: 527

NCBI Accession: NM_001694, NP_001685

UniProt: P27449

Pathways: Transition Metal Ion Homeostasis, Proton Transport