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CD82 Antikörper (PE)

CD82 Reaktivität: Human FACS Wirt: Maus Monoclonal C33 PE
Produktnummer ABIN2749139
  • Target Alle CD82 Antikörper anzeigen
    CD82
    Reaktivität
    • 65
    • 37
    • 6
    • 1
    • 1
    • 1
    Human
    Wirt
    • 59
    • 28
    Maus
    Klonalität
    • 58
    • 29
    Monoklonal
    Konjugat
    • 31
    • 10
    • 8
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD82 Antikörper ist konjugiert mit PE
    Applikation
    • 57
    • 38
    • 28
    • 23
    • 20
    • 19
    • 13
    • 13
    • 8
    • 7
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Spezifität
    The mouse monoclonal antibody C33 recognizes an extracellular/luminal epitope of CD82, a widely expressed cell surface protein of the tetraspanin family. CD82 is also found in endosome/lysosome compartments.
    Kreuzreaktivität (Details)
    Human, Other not tested
    Aufreinigung
    Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
    Immunogen
    C91/PL (human HTLV-1+ T cell line)
    Klon
    C33
    Isotyp
    IgG2a
    Top Product
    Discover our top product CD82 Primärantikörper
  • Applikationshinweise
    Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
    Kommentare

    The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Schatzlmaier, Supper, Göschl, Zwirzitz, Eckerstorfer, Ellmeier, Huppa, Stockinger: "Rapid multiplex analysis of lipid raft components with single-cell resolution." in: Science signaling, Vol. 8, Issue 395, pp. rs11, (2015) (PubMed).

    Escola, Kleijmeer, Stoorvogel, Griffith, Yoshie, Geuze: "Selective enrichment of tetraspan proteins on the internal vesicles of multivesicular endosomes and on exosomes secreted by human B-lymphocytes." in: The Journal of biological chemistry, Vol. 273, Issue 32, pp. 20121-7, (1998) (PubMed).

    Ueda, Ichikawa, Tamaru, Mikata, Akakura, Akimoto, Imai, Yoshie, Shiraishi, Yatani, Ito, Shimazaki: "Expression of the KAI1 protein in benign prostatic hyperplasia and prostate cancer." in: The American journal of pathology, Vol. 149, Issue 5, pp. 1435-40, (1996) (PubMed).

    Imai, Kakizaki, Nishimura, Yoshie: "Molecular analyses of the association of CD4 with two members of the transmembrane 4 superfamily, CD81 and CD82." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 155, Issue 3, pp. 1229-39, (1995) (PubMed).

    Imai, Yoshie et al.: "C33 antigen and M38 antigen recognized by monoclonal antibodies inhibitory to syncytium formation by human T cell leukemia virus type 1 are both members of the transmembrane 4 superfamily and ..." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 151, Issue 11, pp. 6470-81, (1994) (PubMed).

    Fukudome, Furuse, Imai, Nishimura, Takagi, Hinuma, Yoshie et al.: "Identification of membrane antigen C33 recognized by monoclonal antibodies inhibitory to human T-cell leukemia virus type 1 (HTLV-1)-induced syncytium formation: altered glycosylation of C33 antigen ..." in: Journal of virology, Vol. 66, Issue 3, pp. 1394-401, (1992) (PubMed).

  • Target
    CD82
    Andere Bezeichnung
    CD82 (CD82 Produkte)
    Synonyme
    AA682076 antikoerper, AL023070 antikoerper, C33 antikoerper, IA4 antikoerper, Kai1 antikoerper, Tspan27 antikoerper, 4F9 antikoerper, GR15 antikoerper, KAI1 antikoerper, R2 antikoerper, SAR2 antikoerper, ST6 antikoerper, TSPAN27 antikoerper, CD82 antigen antikoerper, CD82 molecule antikoerper, Cd82 molecule antikoerper, Cd82 antikoerper, CD82 antikoerper
    Hintergrund
    CD82 Molecule,CD82 (KAI1), a member of the tetraspanin family, forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules. These complexes influence adhesion, morphology, activation, proliferation and differentiation of B, T and other cells. CD82 regulates cytoskeleton rearrangement and may participate in the turnover of the tetraspanin complex members. Besides in the plasma membrane, CD82 is localized also in endosome/lysosome compartments. Tumour-suppressive roles of CD82 have been demonstrated.,R2, 4F9, C33, IA4, ST6, GR15, KAI1, SAR2, TSPAN27
    Gen-ID
    3732
    UniProt
    P27701
    Pathways
    p53 Signalweg
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