TAG-72 Antikörper

Produktnummer ABIN2744653

Produktdetails anti-TAG-72 Antikörper

Target: TAG-72 (Temporarily Assigned Gene Name Family Member (TAG-72))

Reaktivität: Human, Ratte, Rind (Kuh), Hund, Hamster

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TAG-72 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (IHC), Western Blotting (WB), Immunoprecipitation (IP), ELISA

Spezifität: Human TAG-72

Aufreinigung: Protein G purified

Immunogen: The membrane-enriched fraction of a human breast carcinoma liver metastasis.

Type of Immunogen: Membrane preparation

Klon: B72-3

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Approved: ELISA, Flo (0.5 - 1 μg/10 x10⁶), IF (1 - 2 μg/mL), IHC, IHC-P (0.5 - 1 μg/mL), IP, WB (0.5 - 1 μg/mL)

Usage: This antibody recognizes an oncofetal antigen of 220  kDa, identified as a tumor-associated glycoprotein (TAG-72) with properties of a mucin. This antibody defines the mucin-carried sialylated-Tn epitope. TAG-72 is usually expressed by adenocarcinomas, but is negative in mesotheliomas. Studies have reported that this antibody has 80 % sensitivity and 93 % specificity for pulmonary adenocarcinoma. Therefore, TAG-72 is a useful marker to distinguish between mesothelioma and adenocarcinoma. However, false positive reactions can occur so results must be interpreted with the utmost caution. This antibody may be useful in the differentiation of non-small cell carcinomas from small cell carcinomas of the lung. The combined use of TAG-72 Ab with a GCDFP-15 Ab is valuable in the diagnosis of apocrine carcinoma. ELISA: Order BSA-free format for coating.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS,  pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2°C to 8°C.

Details zu TAG-72

Target: TAG-72 (Temporarily Assigned Gene Name Family Member (TAG-72))

Andere Bezeichnung: TAG-72 (TAG-72 Produkte)

Synonyme: mRNA cap guanine-N7 methyltransferase antikoerper, tag-72 antikoerper

Hintergrund: Name/Gene ID: TAG-72

Synonyms: TAG-72