PSMB7 Antikörper (AA 58-277)
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- Target Alle PSMB7 Antikörper anzeigen
- PSMB7 (Proteasome (Prosome, Macropain) Subunit, beta Type, 7 (PSMB7))
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Bindungsspezifität
- AA 58-277
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Reaktivität
- Human, Maus, Ratte, Affe, Hund
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser PSMB7 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF)
- Produktmerkmale
- Homo sapiens proteasome (prosome, macropain) subunit, beta type, 7 (PSMB7)
- Aufreinigung
- Purified from mouse ascites fluids by affinity chromatography
- Immunogen
- Human recombinant protein fragment corresponding to amino acids 58-277 of human PSMB7(NP_002790) produced in E.coli.
- Klon
- 4G9
- Isotyp
- IgG1
- Top Product
- Discover our top product PSMB7 Primärantikörper
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- Applikationshinweise
- WB 1:1000~2000, IF 1:100,
- Kommentare
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The concentration of the product may vary between diferrent lots.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.5-1.0 mg/mL
- Buffer
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
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- Target
- PSMB7 (Proteasome (Prosome, Macropain) Subunit, beta Type, 7 (PSMB7))
- Andere Bezeichnung
- PSMB7 (PSMB7 Produkte)
- Synonyme
- DDBDRAFT_0185624 antikoerper, DDBDRAFT_0232933 antikoerper, DDB_0185624 antikoerper, DDB_0232933 antikoerper, AU020723 antikoerper, MC14 antikoerper, Z antikoerper, 20S proteasome subunit beta-7 antikoerper, proteasome (prosome, macropain) subunit, beta type, 7 S homeolog antikoerper, proteasome subunit beta 7 antikoerper, proteasome (prosome, macropain) subunit, beta type, 7 antikoerper, proteasome (prosome, macropain) subunit, beta type 7 antikoerper, psmB7 antikoerper, psmb7.S antikoerper, PSMB7 antikoerper, Psmb7 antikoerper
- Hintergrund
- The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit in the proteasome. Expression of this catalytic subunit is downregulated by gamma interferon and proteolytic processing is required to generate a mature subunit. This subunit is not present in the immunoproteasome and is replaced by catalytic subunit 2i (proteasome beta 10 subunit).
- Molekulargewicht
- 29.8 kDa
- Gen-ID
- 5695
- NCBI Accession
- NM_002799
- HGNC
- 5695
- Pathways
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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