CDKL2 Antikörper
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- Target Alle CDKL2 Antikörper anzeigen
- CDKL2 (Cyclin Dependent Kinase Like 2 (CDKL2))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CDKL2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Spezifität
- This antibody detects endogenous levels of KKIAMRE protein. (region surrounding Leu240)
- Kreuzreaktivität (Details)
- Species reactivity (tested):Human.
- Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
- Reinheit
- > 95 % pure by SDS-PAGE
- Top Product
- Discover our top product CDKL2 Primärantikörper
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- Applikationshinweise
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ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1,0 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- DO NOT FREEZE!
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C.
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- Target
- CDKL2 (Cyclin Dependent Kinase Like 2 (CDKL2))
- Andere Bezeichnung
- CDKL2 (CDKL2 Produkte)
- Synonyme
- KKIAMRE antikoerper, P56 antikoerper, CDKL2 antikoerper, 5330436L21Rik antikoerper, AI505225 antikoerper, Kkm antikoerper, DKFZp459L235 antikoerper, kkiamre antikoerper, cyclin dependent kinase like 2 antikoerper, cyclin-dependent kinase-like 2 (CDC2-related kinase) antikoerper, cyclin dependent kinase like 2 L homeolog antikoerper, CDKL2 antikoerper, Cdkl2 antikoerper, cdkl2.L antikoerper
- Hintergrund
- The activation of signal transduction pathways by growth factors, hormones and neurotransmitters is mediated by the MAP kinases ERK 1 and ERK 2. ERK proteins are regulated by dual phosphorylation at specific tyrosine and threonine sites mapping within a characteristic Thr-Glu-Tyr motif. The protein kinase p56 KKIAMRE is distantly related to the MAP kinase group of proteins and is closely related to p42 KKIALRE. KKIAMRE is predominantly expressed in testis, kidney, brain and lung. KKIAMRE contains the conserved MAP kinase dual phosphorylation motif in the sequence Thr-Asp-Tyr and is activated by treatment of cells by EGF. However, unlike other MAP kinases, the EGF-stimulated kinase activity does not require phosphorylation of KKIAMRE and KKIALRE in the Thr-Asp-Tyr motif.Synonyms: Cyclin-dependent kinase-like 2, KKIAMRE, Protein kinase p56 KKIAMRE, Serine/threonine-protein kinase KKIAMRE
- Molekulargewicht
- approx. 56 kDa
- Gen-ID
- 8999
- NCBI Accession
- NP_003939
- UniProt
- Q92772
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