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CDKL2 Antikörper

CDKL2 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN272246
  • Target Alle CDKL2 Antikörper anzeigen
    CDKL2 (Cyclin Dependent Kinase Like 2 (CDKL2))
    Reaktivität
    • 23
    • 11
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 18
    • 5
    Kaninchen
    Klonalität
    • 18
    • 5
    Polyklonal
    Konjugat
    • 16
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CDKL2 Antikörper ist unkonjugiert
    Applikation
    • 16
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Spezifität
    This antibody detects endogenous levels of KKIAMRE protein. (region surrounding Leu240)
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human.
    Aufreinigung
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
    Reinheit
    > 95 % pure by SDS-PAGE
    Top Product
    Discover our top product CDKL2 Primärantikörper
  • Applikationshinweise
    ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1,0 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    DO NOT FREEZE!
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C.
  • Target
    CDKL2 (Cyclin Dependent Kinase Like 2 (CDKL2))
    Andere Bezeichnung
    CDKL2 (CDKL2 Produkte)
    Synonyme
    KKIAMRE antikoerper, P56 antikoerper, CDKL2 antikoerper, 5330436L21Rik antikoerper, AI505225 antikoerper, Kkm antikoerper, DKFZp459L235 antikoerper, kkiamre antikoerper, cyclin dependent kinase like 2 antikoerper, cyclin-dependent kinase-like 2 (CDC2-related kinase) antikoerper, cyclin dependent kinase like 2 L homeolog antikoerper, CDKL2 antikoerper, Cdkl2 antikoerper, cdkl2.L antikoerper
    Hintergrund
    The activation of signal transduction pathways by growth factors, hormones and neurotransmitters is mediated by the MAP kinases ERK 1 and ERK 2. ERK proteins are regulated by dual phosphorylation at specific tyrosine and threonine sites mapping within a characteristic Thr-Glu-Tyr motif. The protein kinase p56 KKIAMRE is distantly related to the MAP kinase group of proteins and is closely related to p42 KKIALRE. KKIAMRE is predominantly expressed in testis, kidney, brain and lung. KKIAMRE contains the conserved MAP kinase dual phosphorylation motif in the sequence Thr-Asp-Tyr and is activated by treatment of cells by EGF. However, unlike other MAP kinases, the EGF-stimulated kinase activity does not require phosphorylation of KKIAMRE and KKIALRE in the Thr-Asp-Tyr motif.Synonyms: Cyclin-dependent kinase-like 2, KKIAMRE, Protein kinase p56 KKIAMRE, Serine/threonine-protein kinase KKIAMRE
    Molekulargewicht
    approx. 56 kDa
    Gen-ID
    8999
    NCBI Accession
    NP_003939
    UniProt
    Q92772
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