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ALX3 Antikörper

ALX3 Reaktivität: Human, Maus, Ratte WB, IF, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN272147
  • Target Alle ALX3 Antikörper anzeigen
    ALX3 (ALX Homeobox 3 (ALX3))
    Reaktivität
    • 25
    • 18
    • 18
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 24
    • 1
    Kaninchen
    Klonalität
    • 24
    • 1
    Polyklonal
    Konjugat
    • 15
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ALX3 Antikörper ist unkonjugiert
    Applikation
    • 14
    • 9
    • 9
    • 6
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Spezifität
    This antibody detects endogenous levels of ALX3 protein. (region surrounding Arg203)
    Kreuzreaktivität (Details)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    Aufreinigung
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
    Reinheit
    > 95 % pure by SDS-PAGE
    Top Product
    Discover our top product ALX3 Primärantikörper
  • Applikationshinweise
    ELISA: 1: 5000approx. 1: 10000. WB: 1: 500approx. 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1,0 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    DO NOT FREEZE!
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C.
  • Target
    ALX3 (ALX Homeobox 3 (ALX3))
    Andere Bezeichnung
    ALX3 (ALX3 Produkte)
    Synonyme
    ALX3 antikoerper, FND1 antikoerper, ALX homeobox 3 antikoerper, aristaless-like homeobox 3 antikoerper, ALX3 antikoerper, Alx3 antikoerper
    Hintergrund
    Aristaless-related genes are a group of paired-related homeobox genes which play a role in regulating vertebrate embryogenesis. The homeodomain transciption factor aristaless-like 3 (ALX3) is expressed in mouse embryos from 8 days of gestation, predominantly in neural crest-derived mesenchyme and in lateral plate mesoderm. Expression analysis of human and mouse tissue reveals predominant ALX3 expression in brain tissue. The Alx3 gene maps to chromosome 1p23-p13 and encodes a 343 amino acid protein. Preferential methylation of Alx3 occurs in advanced-stage neuroblastoma and may repress ALX3 expression. Treatment with the methylation inhibitor 5-aza-2'-deoxycytidine restores ALX3 expression. Alx3 (-) mice lack a phenotype distinct from wild-type mice, however Alx3/Alx4 double mutants demonstrate severe craniofacial abnormalities not present in Alx4 single mutants. Specifically, Alx3/Alx4 double mutant newborn mice have cleft nasal regions in addition to malformation of other neural crest-derived skull structures.Synonyms: Homeobox protein aristaless-like 3, Proline-rich transcription factor ALX3
    Molekulargewicht
    approx. 36 kDa
    Gen-ID
    257
    NCBI Accession
    NP_006483
    UniProt
    O95076
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