FMR1 Antikörper (AA 36-279)

Produktnummer ABIN2721253

Produktdetails anti-FMR1 Antikörper

Target: FMR1 (Fragile X Mental Retardation 1 (FMR1))

Bindungsspezifität: AA 36-279

Reaktivität: Human, Maus, Ratte, Hund, Affe

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser FMR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Produktmerkmale: Homo sapiens fragile X mental retardation 1 (FMR1), transcript variant ISO1

Aufreinigung: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Human recombinant protein fragment corresponding to amino acids 36-279 of human FMR1(NP_002015) produced in E.coli.

Klon: 1C6

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB 1:500~2000, IHC 1:150, IF 1:100, FLOW 1:100,

Kommentare:

The concentration of the product may vary between diferrent lots.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Referenzen für anti-FMR1 Antikörper (ABIN2721253)

Zhou, Ye, Yang, Zhou, Zhao, Sun, Gao, Yi, Long: "A novel role of fragile X mental retardation protein in pre-mRNA alternative splicing through RNA-binding protein 14." in: Neuroscience, Vol. 349, pp. 64-75, (2018) (PubMed).

Details zu FMR1

Target: FMR1 (Fragile X Mental Retardation 1 (FMR1))

Andere Bezeichnung: FMR1 (FMR1 Produkte)

Synonyme: AT24755 antikoerper, BcDNA:GM08679 antikoerper, CG6203 antikoerper, Dmel\\CG6203 antikoerper, EP(3)3517 antikoerper, FMR antikoerper, FMR1 antikoerper, FMRP antikoerper, FMRp antikoerper, FXR antikoerper, Fmrp antikoerper, cg6203 antikoerper, dFMR antikoerper, dFMR1 antikoerper, dFMRP antikoerper, dFXR antikoerper, dFXR1 antikoerper, dFXRP antikoerper, dFmr1 antikoerper, dFmrp antikoerper, dfmr antikoerper, dfmr1 antikoerper, dfxr antikoerper, dfxr1 antikoerper, dmfr1 antikoerper, fmr antikoerper, fmr1 antikoerper, FRAXA antikoerper, POF antikoerper, POF1 antikoerper, zFMR1 antikoerper, Fmr-1 antikoerper, CG6203 gene product from transcript CG6203-RC antikoerper, fragile X mental retardation 1 antikoerper, fragile X mental retardation syndrome 1 antikoerper, Fmr1 antikoerper, FMR1 antikoerper, fmr1 antikoerper

Hintergrund: The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene.

Molekulargewicht: 71 kDa

Gen-ID: 2332

NCBI Accession: NM_002024

HGNC: 2332

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development