NFATC3 Antikörper

Produktnummer ABIN272044

Produktdetails anti-NFATC3 Antikörper

Target: NFATC3 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 3 (NFATC3))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NFATC3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects endogenous levels of NFAT4 protein. (region surrounding Glu159)

Kreuzreaktivität (Details): Species reactivity (tested):Human and Mouse.

Aufreinigung: Affinity Chromatography using epitope-specific immunogen.

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000approx. 1/20000. Western Blot: 1/500approx. 1/1000. Immunohistochemistry: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu NFATC3

Target: NFATC3 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 3 (NFATC3))

Andere Bezeichnung: NFAT4 / NFATC3 (NFATC3 Produkte)

Synonyme: NFATC3 antikoerper, NFATx antikoerper, nf-at antikoerper, nfat4 antikoerper, nfatx antikoerper, C80703 antikoerper, D8Ertd281e antikoerper, NFAT4 antikoerper, NFATX antikoerper, nuclear factor of activated T-cells 3 antikoerper, nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 3 antikoerper, nuclear factor of activated T-cells 3 S homeolog antikoerper, NFATC3 antikoerper, nfatc3 antikoerper, Nfatc3 antikoerper, nfatc3.S antikoerper

Hintergrund: NFATc4 (nuclear factor of activated T cells, cytoplasmic, calcineurindependent 4) is a member of the nuclear factors of activated T cells DNAbinding transcription complex that influences cytokine gene expression, cardiac hypertrophy and adipocyte differentiation. This complex consists of at least two components, a cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family participate in the formation of this complex. NFATc4 plays a role in the inducible expression of cytokine genes in T cells, including the induction of IL-2 and IL-4. p38 MAP kinase phosphorylates multiple residues in the NFAT homology domain of NFATc4.Synonyms: NF-ATc3, NFATc3, Nuclear factor of activated T-cells, T-cell transcription factor NFAT4, T-cell transcription factor NFAT4, cytoplasmic 3

Molekulargewicht: approx. 115 kDa

Gen-ID: 4775

NCBI Accession: NP_004546

UniProt: Q12968

Pathways: RTK Signalweg, WNT Signalweg, Fc-epsilon Rezeptor Signalübertragung, Chromatin Binding