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NCOR1 Antikörper

NCOR1 Reaktivität: Human, Maus WB, IF, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN271948
  • Target Alle NCOR1 Antikörper anzeigen
    NCOR1 (Nuclear Receptor Co-Repressor 1 (NCOR1))
    Reaktivität
    • 56
    • 21
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 51
    • 3
    • 2
    • 1
    Kaninchen
    Klonalität
    • 56
    • 1
    Polyklonal
    Konjugat
    • 29
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser NCOR1 Antikörper ist unkonjugiert
    Applikation
    • 34
    • 28
    • 24
    • 13
    • 13
    • 11
    • 7
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Spezifität
    This antibody detects endogenous levels of NCoR1 protein. (region surrounding His76)
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human, Mouse.
    Aufreinigung
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
    Reinheit
    > 95 % pure by SDS-PAGE
    Top Product
    Discover our top product NCOR1 Primärantikörper
  • Applikationshinweise
    ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1,0 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    DO NOT FREEZE!
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C.
  • Target
    NCOR1 (Nuclear Receptor Co-Repressor 1 (NCOR1))
    Andere Bezeichnung
    NCOR1 (NCOR1 Produkte)
    Synonyme
    ncor antikoerper, zgc:56355 antikoerper, 5730405M06Rik antikoerper, A230020K14Rik antikoerper, N-CoR antikoerper, RIP13 antikoerper, Rxrip13 antikoerper, mKIAA1047 antikoerper, N-CoR1 antikoerper, TRAC1 antikoerper, hN-CoR antikoerper, nuclear receptor corepressor 1 antikoerper, nuclear receptor co-repressor 1 antikoerper, nuclear receptor corepressor 1 pseudogene antikoerper, nuclear receptor corepressor 1 S homeolog antikoerper, ncor1 antikoerper, NCOR1 antikoerper, CpipJ_CPIJ002507 antikoerper, LOC100343278 antikoerper, Ncor1 antikoerper, ncor1.S antikoerper
    Hintergrund
    Retinoids are metabolites of vitamin A (retinol) and are believed to represent important signaling molecules during vertebrate development and tissue differentiation.Two families of retinoid receptors have been identified. Retinoic acid receptors (RARs), include RARα, RARβ and RARγ, each of which have a high affinity for all-trans retinoic acids and belong to the same class of nuclear transcription factors as thyroid hormone receptors, vitamin D3 receptor and ecdysone receptor. Two cofactors that function to repress transcription, designated SMRT and N-CoR, have been shown to associate with the thyroid receptor and RAR in their unliganded state and are released from them upon ligand binding. The carboxy termini of both proteins contain receptor interacting domains while their amino termini contain two previously undescribed repressor domains. SMRT (silencing mediator for RARs and TRs) is 1495 amino acids in length with an estimated molecular weight of 168 kDa. N-CoR (nuclear receptor corepressor) is a protein 2453 amino acids in length with a relative molecular weight of 270 kDa.Synonyms: KIAA1047, N-CoR, N-CoR1, Nuclear receptor corepressor 1
    Molekulargewicht
    approx. 270 kDa
    Gen-ID
    9611
    NCBI Accession
    NP_001177369
    UniProt
    O75376
    Pathways
    Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process
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