DLL4 Antikörper (delta-Like 4) (Internal Region)

Details for Product anti-DLL4 Antibody No. ABIN269907, Anbieter: Anmelden zum Anzeigen
Antigen
  • hdelta2
  • Delta4
  • si:ch211-244p18.5
  • zgc:136596
  • delta like canonical Notch ligand 4
  • delta-like 4 (Drosophila)
  • DLL4
  • Dll4
  • dll4
Epitop
Internal Region
10
10
5
5
4
4
4
4
4
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus)
151
72
46
4
4
4
3
3
3
2
2
1
1
1
Wirt
Kaninchen
85
63
21
13
7
Klonalität
Polyklonal
Konjugat
Dieser DLL4 Antikörper ist unkonjugiert
9
7
6
4
4
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
93
68
64
39
18
13
9
8
6
5
5
4
2
2
2
2
1
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen Synthetic peptide corresponding to an internal region of human DLL4. [UniProt# Q9NR61]
Reinigung Immunogen affinity purified
Plasmids, Primers & others Plasmide, Primers & weitere DLL4 products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung DLL4 (DLL4 Antibody Abstract)
Hintergrund Gene Symbol: DLL4
Gen-ID 54567
UniProt Q9NR61
Pathways Notch Signalweg
Applikations-hinweise Western Blot 1:500-1:2500, ELISA 1:10000 - 1:50000, Immunohistochemistry 10 μg/mL-20 μg/mL, Immunohistochemistry-Paraffin 20 μg/mLExpect a band approximately 74 kDa in size corresponding - DLL4 by western blotting in the appropriate cell lysate or extract.Flow Cytometry was reported in scientific literature.
Kommentare

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1.0 mg/mL
Buffer 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Buffer contains: 0.01 % Sodium Azide
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid freeze-thaw cycles
Lagerung 4 °C,-20 °C
Informationen zur Lagerung Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Bilder des Herstellers
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-delta-Like 4 (DLL4) (Internal Region) antibody (ABIN269907) Immunohistochemistry-Paraffin: DLL4 Antibody [ABIN269907] - This antibody was used at...
Western Blotting (WB) image for anti-delta-Like 4 (DLL4) (Internal Region) antibody (ABIN269907) Western Blot: DLL4 Antibody [ABIN269907] - Shows detection of a 74-kDa band correspon...
Produkt verwendet in: Davis, Kechele, Blakeney, Pawlak, Caron: "Lymphatic deletion of calcitonin receptor-like receptor exacerbates intestinal inflammation." in: JCI insight, Vol. 2, Issue 6, pp. e92465, 2017 (PubMed). Von den Autoren verwendete Methode: Immunofluorescence (fixed cells) (IF/ICC) (Probematerial (Species): Human).

Kontomanolis, Mitrakas, Giatromanolaki, Kareli, Panteliadou, Pouliliou, Koukourakis: "A pilot study on plasma levels of micro-RNAs involved in angiogenesis and vascular maturation in patients with breast cancer." in: Medical oncology (Northwood, London, England), Vol. 34, Issue 2, pp. 20, 2017 (PubMed). Von den Autoren verwendete Methode: Immunohistochemistry (IHC) (Probematerial (Species): Human).

Muguruma, Hozumi, Warita, Yahata, Uno, Ito, Ando: "Maintenance of Bone Homeostasis by DLL1-Mediated Notch Signaling." in: Journal of cellular physiology, Vol. 232, Issue 9, pp. 2569-2580, 2017 (PubMed).

Kontomanolis, Panteliadou, Giatromanolaki, Pouliliou, Efremidou, Limberis, Galazios, Sivridis, Koukourakis: "Delta-like ligand 4 (DLL4) in the plasma and neoplastic tissues from breast cancer patients: correlation with metastasis." in: Medical oncology (Northwood, London, England), Vol. 31, Issue 5, pp. 945, 2014 (PubMed). (Probematerial (Species): Human). Weitere Details: Immunohistochemistry (Paraffin-embedded Sections)

Anjos-Afonso, Currie, Palmer, Foster, Taussig, Bonnet: "CD34(-) cells at the apex of the human hematopoietic stem cell hierarchy have distinctive cellular and molecular signatures." in: Cell stem cell, Vol. 13, Issue 2, pp. 161-74, 2013 (PubMed). (Probematerial (Species): Human). Weitere Details: Immunohistochemistry

Wu, Esumi, Watanabe, Chen, Nakamura, Nakamura, Kometani, Minato, Yanagawa, Akashi, Sakimura, Kaneko, Tamamaki: "Tangential migration and proliferation of intermediate progenitors of GABAergic neurons in the mouse telencephalon." in: Development (Cambridge, England), Vol. 138, Issue 12, pp. 2499-509, 2011 (PubMed).

Zhang, Zeng, Zhang, Jiao, Li, Jing, Ouyang, Yuan, Chai, Che, Zhang, Yang: "Suppressor of cytokine signaling 3 promotes bone marrow cells to differentiate into CD8+ T lymphocytes in lung tissue via up-regulating Notch1 expression." in: Cancer research, Vol. 69, Issue 4, pp. 1578-86, 2009 (PubMed).

Indraccolo, Minuzzo, Masiero, Pusceddu, Persano, Moserle, Reboldi, Favaro, Mecarozzi, Di Mario, Screpanti, Ponzoni, Doglioni, Amadori: "Cross-talk between tumor and endothelial cells involving the Notch3-Dll4 interaction marks escape from tumor dormancy." in: Cancer research, Vol. 69, Issue 4, pp. 1314-23, 2009 (PubMed).

Lipscomb, Chen, Taylor, Goldbach, Watkins, Kalinski, Butterfield, Wesa, Storkus: "Ectopic T-bet expression licenses dendritic cells for IL-12-independent priming of type 1 T cells in vitro." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 183, Issue 11, pp. 7250-8, 2009 (PubMed). (Probematerial (Species): Human). Weitere Details: Flow Cytometry

Gupta, Li, Abedin, Wang, Schneider, Najafian, Rosenberg: "Effect of Notch activation on the regenerative response to acute renal failure." in: American journal of physiology. Renal physiology, Vol. 298, Issue 1, pp. F209-15, 2009 (PubMed). (Probematerial (Species): Rat (Rattus)). Weitere Details: Western Blotting

Su, Mendoza, Kwak, Bayless: "Molecular profile of endothelial invasion of three-dimensional collagen matrices: insights into angiogenic sprout induction in wound healing." in: American journal of physiology. Cell physiology, Vol. 295, Issue 5, pp. C1215-29, 2008 (PubMed). (Probematerial (Species): Human). Weitere Details: Western Blotting

Lauret, Catelain, Titeux, Poirault, Dando, Dorsch, Villeval, Groseil, Vainchenker, Sainteny, Bennaceur-Griscelli: "Membrane-bound delta-4 notch ligand reduces the proliferative activity of primitive human hematopoietic CD34+CD38low cells while maintaining their LTC-IC potential." in: Leukemia, Vol. 18, Issue 4, pp. 788-97, 2004 (PubMed).

Tohda, Murata-Ohsawa, Sakano, Nara: "Notch ligands, Delta-1 and Delta-4 suppress the self-renewal capacity and long-term growth of two myeloblastic leukemia cell lines." in: International journal of oncology, Vol. 22, Issue 5, pp. 1073-9, 2003 (PubMed).

Liu, Shirakawa, Li, Soma, Oka, Dotto, Fairman, Velazquez, Herlyn: "Regulation of Notch1 and Dll4 by vascular endothelial growth factor in arterial endothelial cells: implications for modulating arteriogenesis and angiogenesis." in: Molecular and cellular biology, Vol. 23, Issue 1, pp. 14-25, 2002 (PubMed).

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