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MUC2 Antikörper

MUC2 Reaktivität: Human IHC (f), IHC (fro) Wirt: Maus Monoclonal CCP58 unconjugated
Produktnummer ABIN2689853
  • Target Alle MUC2 Antikörper anzeigen
    MUC2 (Mucin 2, Oligomeric Mucus/gel-Forming (MUC2))
    Reaktivität
    • 64
    • 15
    • 11
    • 2
    Human
    Wirt
    • 55
    • 22
    • 1
    Maus
    Klonalität
    • 43
    • 35
    Monoklonal
    Konjugat
    • 37
    • 12
    • 9
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MUC2 Antikörper ist unkonjugiert
    Applikation
    • 33
    • 32
    • 18
    • 16
    • 14
    • 10
    • 10
    • 8
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Marke
    BD Pharmingen™
    Produktmerkmale
    Reacts with the core peptide of the MUC2 protein, a member of a family of mucin glycoproteins that are characterized by high carbohydrate content, O-linked oligosaccharides, high molecular weight (>200 kD) and an amino acid composition rich in serine, threonin, proline and glycine. The core protein contains a domain of 23 amino-acid tandem repeats which function as multiple epitopes for the monoclonal antibody. Incomplete glycosylation of some tumor-associated mucins may lead to variable unmasking of the multiple peptide epitopes leading to the observed differences in staining intensity between normal and malignant tissues. This antibody has been shown to be relatively tissue specific, being associated predominantly with intestinal tissue and is highly reactive with colon and gastric tumors. The antibody is suitable for staining formalin-fixed, paraffin-embedded tissue sections following citrate pretreatment.

    BD Pharmingen™ Purified Mouse Anti-Human MUC2 - Purified - Clone CCP58 - Isotype Mouse IgG1, κ - Reactivity Hu - 0.1 mg
    Aufreinigung
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Klon
    CCP58
    Isotyp
    IgG1 kappa
    Top Product
    Discover our top product MUC2 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 mg/mL
    Buffer
    Aqueous buffered solution containing ≤0.09 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store undiluted at 4°C.
  • Devine, Birrell, Whitehead, Harada, Xing, McKenzie: "Expression of MUC1 and MUC2 mucins by human tumor cell lines." in: Tumour biology, Vol. 13, Issue 5-6, pp. 268-77, (1993) (PubMed).

    Xing, Prenzoska, Layton, Devine, McKenzie: "Second-generation monoclonal antibodies to intestinal MUC2 peptide reactive with colon cancer." in: Journal of the National Cancer Institute, Vol. 84, Issue 9, pp. 699-703, (1992) (PubMed).

  • Target
    MUC2 (Mucin 2, Oligomeric Mucus/gel-Forming (MUC2))
    Andere Bezeichnung
    MUC2 (MUC2 Produkte)
    Synonyme
    2010015E03Rik antikoerper, MCM antikoerper, wnn antikoerper, MLP antikoerper, MUC-2 antikoerper, SMUC antikoerper, HH-Muc antikoerper, mucin 2 antikoerper, mucin 2, oligomeric mucus/gel-forming antikoerper, mucin-2 antikoerper, Muc2 antikoerper, MUC2 antikoerper, LOC100724045 antikoerper
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