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VEGFR2/CD309 Antikörper

VEGFR2 Reaktivität: Maus FACS, IHC (fro), IHC (f) Wirt: Ratte Monoclonal Avas 12alpha1 unconjugated
Produktnummer ABIN2689505
  • Target Alle VEGFR2/CD309 (VEGFR2) Antikörper anzeigen
    VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))
    Reaktivität
    • 314
    • 204
    • 145
    • 18
    • 9
    • 7
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Maus
    Wirt
    • 309
    • 55
    • 17
    • 2
    • 1
    • 1
    • 1
    Ratte
    Klonalität
    • 304
    • 82
    Monoklonal
    Konjugat
    • 166
    • 35
    • 21
    • 15
    • 15
    • 13
    • 13
    • 13
    • 11
    • 11
    • 11
    • 11
    • 6
    • 6
    • 6
    • 6
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser VEGFR2/CD309 Antikörper ist unkonjugiert
    Applikation
    • 241
    • 137
    • 101
    • 90
    • 63
    • 34
    • 26
    • 24
    • 24
    • 13
    • 13
    • 12
    • 9
    • 7
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    Marke
    BD Pharmingen™
    Produktmerkmale
    The Avas 12α1 monoclonal antibody specifically binds to fetal liver kinase 1 (Flk-1), a receptor protein tyrosine kinase closely related to CD117 (c-kit) and CD140a (PDGF Receptor α chain) of the immunoglobulin superfamily. Flk-1, also known as VEGF Receptor-2 (VEGF-R2), is a receptor for vascular endothelial growth factor (VEGF). It is expressed, at the mRNA and protein levels, on distinct sets of mesoderm during gastrulation and on endothelial cells in embryonic and adult tissues. In vivo and in vitro studies indicate that Flk-1 is required for the embryonic development of vascular endothelial and hematopoietic cells. Immunohistochemical staining of mouse Flk-1. Frozen sections of normal mouse spleen were reacted with the anti-Flk-1 antibody. Endothelial cells expressing Flk-1 can be identified by the brown labeling of their cell membranes. Amplification 20X.

    BD Pharmingen™ Purified Rat Anti-Mouse Flk-1 - Purified - Clone Avas 12alpha1 - Isotype Rat IgG2a, κ - Reactivity Ms - 1 mL
    Aufreinigung
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Immunogen
    Mouse Flk-1 Recombinant Protein
    Klon
    Avas 12alpha1
    Isotyp
    IgG2a kappa
    Top Product
    Discover our top product VEGFR2 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    31.25 μg/mL
    Buffer
    Aqueous buffered solution containing BSA, goat serum, and ≤0.09 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store undiluted at 4°C.
  • Nishikawa, Nishikawa, Kawamoto, Yoshida, Kizumoto, Kataoka, Katsura: "In vitro generation of lymphohematopoietic cells from endothelial cells purified from murine embryos." in: Immunity, Vol. 8, Issue 6, pp. 761-9, (1998) (PubMed).

    Hanahan: "Signaling vascular morphogenesis and maintenance." in: Science (New York, N.Y.), Vol. 277, Issue 5322, pp. 48-50, (1997) (PubMed).

    Shalaby, Ho, Stanford, Fischer, Schuh, Schwartz, Bernstein, Rossant: "A requirement for Flk1 in primitive and definitive hematopoiesis and vasculogenesis." in: Cell, Vol. 89, Issue 6, pp. 981-90, (1997) (PubMed).

    Shalaby, Rossant, Yamaguchi, Gertsenstein, Wu, Breitman, Schuh: "Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice." in: Nature, Vol. 376, Issue 6535, pp. 62-6, (1995) (PubMed).

    Millauer, Wizigmann-Voos, Schnürch, Martinez, Møller, Risau, Ullrich: "High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis." in: Cell, Vol. 72, Issue 6, pp. 835-46, (1993) (PubMed).

  • Target
    VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))
    Andere Bezeichnung
    Flk-1 (VEGFR2 Produkte)
    Synonyme
    CD309 antikoerper, FLK1 antikoerper, VEGFR antikoerper, VEGFR2 antikoerper, 6130401C07 antikoerper, Flk-1 antikoerper, Flk1 antikoerper, Krd-1 antikoerper, Ly73 antikoerper, VEGFR-2 antikoerper, sVEGFR-2 antikoerper, Vegfr-2 antikoerper, FLK-1 antikoerper, flk-1 antikoerper, vegfr-2 antikoerper, KDR antikoerper, FLK/KDR antikoerper, flk1 antikoerper, flk1b antikoerper, kdrb antikoerper, si:busm1-205d10.1 antikoerper, si:ch211-254j6.1 antikoerper, si:ch211-278f21.4 antikoerper, wu:fc31a09 antikoerper, fk52c05 antikoerper, flk antikoerper, kdr antikoerper, kdra antikoerper, vegfr2 antikoerper, vegfr4 antikoerper, vegr2 antikoerper, wu:fk52c05 antikoerper, kinase insert domain receptor antikoerper, kinase insert domain protein receptor antikoerper, vascular endothelial growth factor receptor kdr-like antikoerper, kinase insert domain receptor (a type III receptor tyrosine kinase) antikoerper, kinase insert domain receptor like antikoerper, KDR antikoerper, Kdr antikoerper, LOC100136647 antikoerper, kdr antikoerper, kdrl antikoerper
    Hintergrund
    Synonyms: Fetal liver kinase 1, CD309, Kdr, VEGF receptor-2, VEGFR-2
    Pathways
    RTK Signalweg, Glycosaminoglycan Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling
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