CEACAM1 Antikörper

Produktnummer ABIN2689373

Produktdetails anti-CEACAM1 Antikörper

Target: CEACAM1 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CEACAM1 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Marke: BD Pharmingen™

Produktmerkmale: Reacts with several glycosylphosphatidylinositol-anchored glycoproteins present on granulocytes and epithelial cells. Antibody B1.1 was studied as recognizing CD66a, c, d and e in the VI Human Leukocyte Differentiation Workshop. CD66 antigens, also known as the carcinoembryonic antigen (CEA) family of molecules, are closely related to the immunoglobulin superfamily of glycoproteins. Studies on CD66 Molecules suggest a potential adhesion function in vivo. These molecules exhibit both homophilic and heterophilic ashesion. CEA family members may be involved in transmembrane signalling and activation of neutrophils. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of peripheral blood granulocytes analyzed by flow cytometry. Second step staining with Cat. No. 555988.

BD Pharmingen™ Purified Mouse Anti-Human CD66 - Purified - Clone B1.1/CD66 - Isotype Mouse IgG2a, κ - Reactivity Hu - 0.1 mg

Aufreinigung: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Klon: B1-1-CD66

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store undiluted at 4°C.

Referenzen für anti-CEACAM1 Antikörper (ABIN2689373)

Nagel, Grunert, Kuijpers, Watt, Thompson, Zimmermann: "Genomic organization, splice variants and expression of CGM1, a CD66-related member of the carcinoembryonic antigen gene family." in: European journal of biochemistry / FEBS, Vol. 214, Issue 1, pp. 27-35, (1993) (PubMed).

Kuroki, Arakawa, Matsuo, Oikawa, Misumi, Nakazato, Matsuoka: "Molecular cloning of nonspecific cross-reacting antigens in human granulocytes." in: The Journal of biological chemistry, Vol. 266, Issue 18, pp. 11810-7, (1991) (PubMed).

Thompson, Grunert, Zimmermann: "Carcinoembryonic antigen gene family: molecular biology and clinical perspectives." in: Journal of clinical laboratory analysis, Vol. 5, Issue 5, pp. 344-66, (1991) (PubMed).

Szpak, Johnston, Lottich, Kufe, Thor, Schlom: "Patterns of reactivity of four novel monoclonal antibodies (B72.3, DF3, B1.1 and B6.2) with cells in human malignant and benign effusions." in: Acta cytologica, Vol. 28, Issue 4, pp. 356-67, (1984) (PubMed).

Details zu CEACAM1

Target: CEACAM1 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1))

Andere Bezeichnung: CD66 (CEACAM1 Produkte)

Synonyme: BGP antikoerper, BGP1 antikoerper, BGPI antikoerper, CD66e antikoerper, CEA antikoerper, zeh0068 antikoerper, hm:zeh0068 antikoerper, CEACAM8 antikoerper, CEACAM1 antikoerper, MGC142545 antikoerper, BGPR antikoerper, Bgp antikoerper, CD66a antikoerper, Ccam1 antikoerper, Bgp1 antikoerper, C-CAM antikoerper, Cc1 antikoerper, Cea-1 antikoerper, Cea-7 antikoerper, Cea1 antikoerper, Cea7 antikoerper, Hv-2 antikoerper, Hv2 antikoerper, MHVR antikoerper, MHVR1 antikoerper, Mhv-1 antikoerper, bb-1 antikoerper, mCEA1 antikoerper, mmCGM1 antikoerper, mmCGM1a antikoerper, mmCGM2 antikoerper, carcinoembryonic antigen related cell adhesion molecule 1 antikoerper, carcinoembryonic antigen related cell adhesion molecule 5 antikoerper, carcinoembryonic antigen-related cell adhesion molecule 1 antikoerper, carcinoembryonic antigen-related cell adhesion molecule 6 antikoerper, CEACAM1 antikoerper, CEACAM5 antikoerper, ceacam1 antikoerper, Ceacam1 antikoerper, LOC101103343 antikoerper

Hintergrund: Synonyms: CEA, carcinoembryonic antigen