Integrin alpha 2 (ITGA2) Antikörper

Details zu Produkt Nr. ABIN2689303
Antigen
  • BR
  • CD49B
  • GPIa
  • HPA-5
  • VLA-2
  • VLAA2
  • DX5
  • integrin subunit alpha 2
  • integrin alpha 2
  • ITGA2
  • Itga2
Reaktivität
Maus, Ratte (Rattus)
248
134
28
20
11
11
10
4
3
3
3
2
1
1
1
1
Wirt
Armenischer Hamster
129
122
82
10
1
Klonalität (Klon)
Monoklonal ()
Konjugat
Unkonjugiert
47
33
31
16
6
5
5
5
5
3
3
3
3
2
2
2
2
2
2
Applikation
Blocking Reagent (BR), Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS), Immunoprecipitation (IP)
197
114
79
73
38
26
21
21
14
11
10
4
3
2
1
1
Optionen
Marke BD Pharmingen™
Immunogen Cultured Rat Glomerular Epithelial
Klon Ha1-29
Isotyp IgG2, lambda
Produktmerkmale The Ha1/29 antibody reacts with intergrin α2 chain (CD49b or VLA-2 α chain), the 160- kDa transmembrane glycoprotein that non-covalently associates with the intergrin β1 subunit (CD29) to form the intergrin α2β1 complex known as VLA-2. VLA-2, a receptor for collagen and laminin, is expressed on activated lymphocytes, epithelial cells, and platelets. It has been reported that Ha1/29 antibody can block VLA-2 binding to collagen and laminin. Ha1/29 antibody also reacts with mouse CD49b. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature.

BD Pharmingen™ Purified Hamster Anti-Rat CD49b - Purified - Clone Ha1/29 - Isotype Armenian Hamster IgG2, λ - Reactivity Rat, Ms - 0.1 mg
Reinigung The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Antigen
Andere Bezeichnung CD49b (ITGA2 Antibody Abstract)
Hintergrund Synonyms: Integrin α2 chain
Pathways CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Integrin Complex
Applikations-hinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 0.5 mg/mL
Buffer Aqueous buffered solution containing ≤0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store undiluted at 4°C.
Produkt verwendet in: Mendrick, Kelly, duMont, Sandstrom: "Glomerular epithelial and mesangial cells differentially modulate the binding specificities of VLA-1 and VLA-2." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 72, Issue 3, pp. 367-75, 1995 (PubMed).

Mendrick, Kelly: "Temporal expression of VLA-2 and modulation of its ligand specificity by rat glomerular epithelial cells in vitro." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 69, Issue 6, pp. 690-702, 1994 (PubMed).

Hemler: "VLA proteins in the integrin family: structures, functions, and their role on leukocytes." in: Annual review of immunology, Vol. 8, pp. 365-400, 1990 (PubMed).

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