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CD200 Antikörper

CD200 Reaktivität: Maus FACS, IHC, ELISA Wirt: Ratte Monoclonal OX unconjugated
Produktnummer ABIN2689079
  • Target Alle CD200 Antikörper anzeigen
    CD200
    Reaktivität
    • 93
    • 25
    • 22
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Maus
    Wirt
    • 57
    • 50
    • 15
    Ratte
    Klonalität
    • 60
    • 59
    Monoklonal
    Konjugat
    • 41
    • 14
    • 14
    • 11
    • 9
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD200 Antikörper ist unkonjugiert
    Applikation
    • 56
    • 55
    • 33
    • 26
    • 16
    • 14
    • 13
    • 10
    • 8
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA
    Marke
    BD Pharmingen™
    Produktmerkmale
    The OX-90 antibody reacts with CD200 (OX-2 antigen), a type-1 membrane glycoprotein containing two extracellular Ig-like domains. CD200 is expressed on thymocytes, neurons, B lymphocytes, splenic follicular dendritic cells and endothelium, and subsets of T lymphocytes and dendritic cells, but not on NK cells, granulocytes, monocytes, or macrophages. The CD200 Receptor is restricted to myeloid cells, and it is believed that its engagement with CD200 results in inhibition and/or down-regulation of myeloid cell activity. Multi-color analysis of the expression of CD200 on thymocytes. C57BL/6 thymocytes were stained with either purified mAb OX-90 (open histograms) or purified rat IgG2a, κ isotype control mAb R35-95 (Cat. No. 553927, shaded histograms), followed by biotinylated anti-rat IgG2a mAb RG7/1.30 (Cat. No. 553894) then Streptavidin-PE (Cat. No. 554061). Then the cells were stained with FITC-conjugated anti-mouse CD4 mAb and APC-conjugated anti-mouse CD8a mAb 53-6.7 (Cat. No. 553035). Electronic gates were set to include the CD4-CD8a-, CD4+CD8a+, CD4+CD8a-, and CD4-CD8a+ populations, and their expression of CD200 is displayed in the corresponding panels. Flow cytometry was performed on a BD FACSCalibur™

    BD Pharmingen™ Purified Rat Anti-Mouse CD200 - Purified - Clone OX-90 - Isotype Rat IgG2a, κ - Reactivity Ms - 0.5 mg
    Aufreinigung
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Immunogen
    Soluble fusion protein of the extracellular region of mouse OX-2 antigen w/domains 3 & 4 of rat CD4
    Klon
    OX
    Isotyp
    IgG2a kappa
    Top Product
    Discover our top product CD200 Primärantikörper
  • Applikationshinweise
    Flow Cytometry System.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 mg/mL
    Buffer
    Aqueous buffered solution containing ≤0.09 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store undiluted at 4°C.
  • Hoek, Ruuls, Murphy, Wright, Goddard, Zurawski, Blom, Homola, Streit, Brown, Barclay, Sedgwick: "Down-regulation of the macrophage lineage through interaction with OX2 (CD200)." in: Science (New York, N.Y.), Vol. 290, Issue 5497, pp. 1768-71, (2000) (PubMed).

    Gorczynski, Chen, Hu, Kai, Lei, Ramakrishna, Gorczynski: "Evidence that an OX-2-positive cell can inhibit the stimulation of type 1 cytokine production by bone marrow-derived B7-1 (and B7-2)-positive dendritic cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 162, Issue 2, pp. 774-81, (1999) (PubMed).

    Preston, Wright, Starr, Barclay, Brown: "The leukocyte/neuron cell surface antigen OX2 binds to a ligand on macrophages." in: European journal of immunology, Vol. 27, Issue 8, pp. 1911-8, (1997) (PubMed).

  • Target
    CD200
    Andere Bezeichnung
    CD200 (CD200 Produkte)
    Synonyme
    MOX1 antikoerper, MOX2 antikoerper, MRC antikoerper, OX-2 antikoerper, CD200 antikoerper, Cspmo2 antikoerper, MRCOX2 antikoerper, Mox2 antikoerper, DKFZp459C0716 antikoerper, OX2 antikoerper, CD200 molecule antikoerper, Cd200 molecule antikoerper, CD200 antigen antikoerper, CD200 antikoerper, Cd200 antikoerper
    Hintergrund
    Synonyms: OX-2 Antigen
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