PVRL2 Antikörper

Produktnummer ABIN2688890

Produktdetails anti-PVRL2 Antikörper

Target: PVRL2 (Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PVRL2 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Marke: BD Pharmingen™

Produktmerkmale: Reacts with the poliovirus receptor 2 (PRR2) protein. PRR2 is a cell surface molecule homologous to the poliovirus receptor (PVR/CD155). It is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The PRR2 gene encodes for two mRNA isoforms, a short form of 3.0 kb (hPRR2α) and a long form of 4.4 kb (hPRR2δ). Both are widely expressed in human tissues, including hematopoietic cells. PRR2 is also expressed on endothelial cells, at the intercellular junctions of adjacent cells. It has been suggested that PRR2 may play a role in the regulation of hematopoietic/endothelial cell interaction. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of HL-60 cell line analyzed by flow cytometry. Second step staining with Cat. No. 555988.

BD Pharmingen™ Purified Mouse Anti-Human CD112 - Purified - Clone R2.525 - Isotype Mouse IgG1, κ - Reactivity Hu - 0.1 mg

Aufreinigung: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Klon: R2-525

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store undiluted at 4°C.

Referenzen für anti-PVRL2 Antikörper (ABIN2688890)

Lopez, Aoubala, Jordier, Isnardon, Gomez, Dubreuil: "The human poliovirus receptor related 2 protein is a new hematopoietic/endothelial homophilic adhesion molecule." in: Blood, Vol. 92, Issue 12, pp. 4602-11, (1999) (PubMed).

Eberlé, Dubreuil, Mattei, Devilard, Lopez: "The human PRR2 gene, related to the human poliovirus receptor gene (PVR), is the true homolog of the murine MPH gene." in: Gene, Vol. 159, Issue 2, pp. 267-72, (1995) (PubMed).

Details zu PVRL2

Target: PVRL2 (Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2))

Andere Bezeichnung: CD112 (PVRL2 Produkte)

Synonyme: prr2 antikoerper, AI325026 antikoerper, AI987993 antikoerper, Cd112 antikoerper, MPH antikoerper, Pvr antikoerper, Pvs antikoerper, nectin-2 antikoerper, CD112 antikoerper, HVEB antikoerper, PRR2 antikoerper, PVRR2 antikoerper, nectin cell adhesion molecule 2 antikoerper, Nectin2 antikoerper, NECTIN2 antikoerper

Hintergrund: Synonyms: PRR2

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization