Myc Tag (AA 410-419) Antikörper

Details zu Produkt Nr. ABIN2688145, Anbieter: Anmelden zum Anzeigen
Antigen
  • MRTL
  • MYCC
  • bHLHe39
  • c-Myc
  • ARC
  • B430311C09Rik
  • MYC
  • NOP
  • Nop30
  • MYC proto-oncogene, bHLH transcription factor
  • nucleolar protein 3 (apoptosis repressor with CARD domain)
  • MYC
  • Nol3
Epitop
AA 410-419
55
20
18
10
6
4
2
2
2
2
1
1
Reaktivität
Tag
211
58
14
12
6
5
3
1
1
Wirt
Maus
166
64
20
17
6
5
3
1
Klonalität (Klon)
Monoklonal ()
Konjugat
Unkonjugiert
28
24
15
9
5
5
4
4
4
4
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Cell Culture (CC), Dot Blot (DB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), ELISA, Western Blotting (WB)
239
117
94
68
50
38
36
36
23
7
6
5
5
4
4
3
3
3
3
2
1
1
1
1
1
1
Optionen
Hersteller
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Immunogen A synthetic peptide corresponding to residues 410-419 (EQKLISEEDL) coupled to KLH.
Sequenz EQKLISEEDL
Klon Myc-A7
Isotyp IgG1
Spezifität Myc-tag Monoclonal Antibody. Recognises over-expressed proteins containing Myc epitope tag fused to either amino- or carboxy-termini of targeted proteins in transfected mammalian cells.
Substanzklasse Tag
Hintergrund This gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq, Jul 2008]
Applikationshinweise Western Blot (1:1000), Immunoprecipitation and Immunostaining (1:200). Other dilutions will need optimization by end user.
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer PBS, pH 7.4 with 0.05 % sodium azide.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C,-20 °C
Produkt verwendet in: Jo, Kim, Son: "Erythropoietin and carbamylated erythropoietin promote histone deacetylase 5 phosphorylation and nuclear export in rat hippocampal neurons." in: Biochemical and biophysical research communications, Vol. 470, Issue 1, pp. 220-5, 2016 (PubMed). Von den Autoren verwendete Methode: Western Blotting (WB)

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