Prelamin A (C-Term), (cleaved), (farnesylated) Antikörper
Reaktivität: Human
IF
Wirt: Kaninchen
Polyclonal
unconjugated
-
- Target
- Prelamin A
- Bindungsspezifität
- C-Term, cleaved, farnesylated
- Reaktivität
- Human
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Unkonjugiert
-
Applikation
- Immunofluorescence (IF)
- Spezifität
- Anti cleaved farnesylated prelamin A polyclonal antibody detects carboxymethylated prelamin A harbouring the farnesyl residue. This antibody also recognizes progerin, the truncated form of prelamin A found in HutchinsonGilford Progeria Syndrome cells, and does not cross react with mature lamin A.
- Produktmerkmale
- The antibody is able to detect cleaved farnesylated prelamin A, while it does not recognize either full-length prelamin A or mature lamin A. This antibody can be used for the discrimination of prelamin A forms and to check the efficacy of potential therapeutic compounds acting on prelamin A processing.
- Aufreinigung
- Polyclonal immunoglobulins purified by protein A affinity chromatography and stabilized with 5% of glycerol.
- Immunogen
- Farnesylated prelamin A C-terminus peptide
-
-
- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Kommentare
-
methanol fixing is suggested
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Buffer
- Supplied in 100 mM sodium citrate, 50 mM Tris and 0.05 % v/v glycerol
- Lagerung
- 4 °C
-
- Target
- Prelamin A
-
Sie sind hier:
