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MLL/KMT2A Antikörper (AA 2829-2883)

MLL Reaktivität: Human, Maus WB, ChIP, ICC, ChIP-seq, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2668494
  • Target Alle MLL/KMT2A (MLL) Antikörper anzeigen
    MLL/KMT2A (MLL) (Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL))
    Bindungsspezifität
    • 8
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2829-2883
    Reaktivität
    • 30
    • 11
    • 9
    Human, Maus
    Wirt
    • 25
    • 5
    Kaninchen
    Klonalität
    • 26
    • 4
    Polyklonal
    Konjugat
    • 18
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MLL/KMT2A Antikörper ist unkonjugiert
    Applikation
    • 16
    • 14
    • 14
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Chromatin Immunoprecipitation (ChIP), Immunocytochemistry (ICC), ChIP DNA-Sequencing (ChIP-seq), Immunofluorescence (IF)
    Aufreinigung
    Protein A Chromatography
    Immunogen
    This MLL / HRX antibody was raised against a recombinant protein corresponding to amino acids 2829-2883 of human MLL.
    Isotyp
    IgG
    Top Product
    Discover our top product MLL Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1 μg/μL
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung

    Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

    Lagerung
    -20 °C
    Informationen zur Lagerung
    Antibodies in solution can be stored at -20 °C for 2 years.
    Haltbarkeit
    6 months
  • Kühn, Löscher, Marschalek: "The IRX1/HOXA connection: insights into a novel t(4;11)- specific cancer mechanism." in: Oncotarget, Vol. 7, Issue 23, pp. 35341-52, (2016) (PubMed).

    Kang, Piao, Ryu, Kang, Chang, Keum, Hyun: "Interaction of DNA demethylase and histone methyltransferase upregulates Nrf2 in 5-fluorouracil-resistant colon cancer cells." in: Oncotarget, Vol. 7, Issue 26, pp. 40594-40620, (2016) (PubMed).

    Ahmad, Katryniok, Scholz, Merkens, Löscher, Marschalek, Steinhilber: "Inhibition of class I HDACs abrogates the dominant effect of MLL-AF4 by activation of wild-type MLL." in: Oncogenesis, Vol. 3, pp. e127, (2014) (PubMed).

    Pradeepa, Grimes, Taylor, Sutherland, Bickmore: "Psip1/Ledgf p75 restrains Hox gene expression by recruiting both trithorax and polycomb group proteins." in: Nucleic acids research, Vol. 42, Issue 14, pp. 9021-32, (2014) (PubMed).

    Wilkinson, Ballabio, Geng, North, Tapia, Kerry, Biswas, Roeder, Allis, Melnick, de Bruijn, Milne: "RUNX1 is a key target in t(4;11) leukemias that contributes to gene activation through an AF4-MLL complex interaction." in: Cell reports, Vol. 3, Issue 1, pp. 116-27, (2013) (PubMed).

  • Target
    MLL/KMT2A (MLL) (Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL))
    Andere Bezeichnung
    MLL / HRX (MLL Produkte)
    Synonyme
    ALL-1 antikoerper, CXXC7 antikoerper, HRX antikoerper, HTRX1 antikoerper, MLL antikoerper, MLL/GAS7 antikoerper, MLL1A antikoerper, TET1-MLL antikoerper, TRX1 antikoerper, WDSTS antikoerper, 6430520K01 antikoerper, All1 antikoerper, Cxxc7 antikoerper, Mll antikoerper, Mll1 antikoerper, mKIAA4050 antikoerper, lysine methyltransferase 2A antikoerper, lysine (K)-specific methyltransferase 2A antikoerper, KMT2A antikoerper, Kmt2a antikoerper
    Molekulargewicht
    180 kDa
    Gen-ID
    4297
    Pathways
    Warburg Effekt
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