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CD51/CD61 Antikörper (FITC)

ITGAV/ITGB3 Reaktivität: Human FACS Wirt: Maus Monoclonal 23C6 FITC
Produktnummer ABIN2661770
  • Target Alle CD51/CD61 (ITGAV/ITGB3) Antikörper anzeigen
    CD51/CD61 (ITGAV/ITGB3) (Integrin AlphaV, Integrin Beta3 (ITGAV/ITGB3))
    Reaktivität
    • 34
    • 20
    • 20
    • 9
    • 6
    • 5
    • 5
    • 5
    • 5
    • 2
    Human
    Wirt
    • 20
    • 14
    Maus
    Klonalität
    • 20
    • 14
    Monoklonal
    Konjugat
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD51/CD61 Antikörper ist konjugiert mit FITC
    Applikation
    • 28
    • 22
    • 13
    • 13
    • 9
    • 7
    • 6
    • 6
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Kreuzreaktivität
    Kaninchen, Huhn
    Aufreinigung
    The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC.
    Klon
    23C6
    Isotyp
    IgG1 kappa
    Top Product
    Discover our top product ITGAV/ITGB3 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Protect from prolonged exposure to light. Do not freeze.
    Lagerung
    4 °C
    Informationen zur Lagerung
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    CD51/CD61 (ITGAV/ITGB3) (Integrin AlphaV, Integrin Beta3 (ITGAV/ITGB3))
    Andere Bezeichnung
    CD51/61 (ITGAV/ITGB3 Produkte)
    Synonyme
    CD51 antikoerper, MSK8 antikoerper, VNRA antikoerper, VTNR antikoerper, integrin subunit alpha V antikoerper, ITGAV antikoerper
    Hintergrund
    CD51/CD61 is an integrin complex known as αVβ3. It is expressed at high levels on osteoclasts, endothelial cells, and melanoma cells and at low levels on platelets and macrophages. CD51 is a heterodimer composed of disulfide-linked 125 kD and 24 kD proteins. CD61 is also a member of the integrin family known as gpIIIa or β3 integrin. It is a 110 kD common β subunit of CD51/CD61 or CD41/CD61 complex. CD51/CD61, also known as the vitronectin receptor, mediates the binding of platelets to immobilized vitronectin without prior activation. Other ligands include RGD-containing proteins such as fibrinogen, fibronectin, von Willebrand factor (vWf), laminin, thrombospondin and the neural adhesion molecule L1. CD51/CD61 also mediates cell-cell adhesion via interaction with CD31. CD51/CD61 acts as an activation-independent receptor for platelet attachment and spreading on vitronectin and other RGD-containing proteins, including matrix components. The 23C6 antibody has been reported to be useful for blocking studies.
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