MMP19 Antikörper

Produktnummer ABIN265528

Produktdetails anti-MMP19 Antikörper

Target: MMP19 (Matrix Metallopeptidase 19 (MMP19))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MMP19 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects endogenous levels of MMP-19 protein. (region surrounding Gly44)

Kreuzreaktivität (Details): Species reactivity (tested):Human, Mouse.

Aufreinigung: Affinity Chromatography using epitope-specific immunogen

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu MMP19

Target: MMP19 (Matrix Metallopeptidase 19 (MMP19))

Andere Bezeichnung: MMP-19 (MMP19 Produkte)

Synonyme: mmp18 antikoerper, mmp-18 antikoerper, mmp-19 antikoerper, col4 antikoerper, MMP18 antikoerper, RASI-1 antikoerper, matrix metallopeptidase 19 antikoerper, matrix metallopeptidase 1 S homeolog antikoerper, mmp19 antikoerper, mmp1.S antikoerper, MMP19 antikoerper, Mmp19 antikoerper

Hintergrund: The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-13 (also designated collagenase-3) is produced by breast carcinomas and degrades collagen types I, II and III. MMP-13 has wide substrate specificity, and its physiologic expression is limited to situations in which rapid and effective remodeling of collagenous ECM takes place, such as fetal bone development and adult bone remodeling.Synonyms: MMP-18, MMP18, MMP19, Matrix metalloproteinase RASI, Matrix metalloproteinase-19, RASI

Molekulargewicht: approx. 57 kDa

Gen-ID: 4327

NCBI Accession: NP_002420

UniProt: Q99542