LNX1 Antikörper

Produktnummer ABIN265233

Produktdetails anti-LNX1 Antikörper

Target: LNX1 (Ligand of Numb-Protein X 1 (LNX1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LNX1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: This antibody detects LNX1, expressed in heart, placenta, kidney, pancreas and brain.

Aufreinigung: Purified

Immunogen: Synthetic peptide derived from the human LNX1 protein

Anwendungsinformationen

Applikationshinweise: Western blot: (1-5 μg/mL).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Phosphate buffered saline with 0.08 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the product (in aliquots) at -20 °C. Can be shipped at 2 - 8 °C.

Details zu LNX1

Target: LNX1 (Ligand of Numb-Protein X 1 (LNX1))

Andere Bezeichnung: LNX1 (LNX1 Produkte)

Synonyme: LNX1 antikoerper, fj78f06 antikoerper, lnx antikoerper, si:dkey-12h2.1 antikoerper, wu:fj78f06 antikoerper, zgc:152906 antikoerper, Lnx antikoerper, LNX antikoerper, MPDZ antikoerper, PDZRN2 antikoerper, ligand of numb-protein X 1 antikoerper, LNX1 antikoerper, lnx1 antikoerper, Lnx1 antikoerper

Hintergrund: LNX1 is an E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of NUMB. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates ubiquitination of isoform p66 and isoform p72 of NUMB, but not that of isoform p71 or isoform p65Synonyms: E3 ubiquitin-protein ligase LNX, LNX, LNX-1, Ligand of Numb-protein X 1, Numb-binding protein 1

Gen-ID: 84708

NCBI Accession: NP_001119800

UniProt: Q8TBB1